1 HAMP#1
278-346 aa · 69 aa · 12.0% of protein
Raw token
HAMP:278:0.000000267:346:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS03425
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength577 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466465#HMPREF1548_RS03425Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length577 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 577 aa (43.0%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa577 aa
Domain-by-domain annotation3 items
2 His_kinase#2
363-435 aa · 73 aa · 12.7% of protein
Raw token
His_kinase:363:8.59e-19:435:73:803 HATPase_c#3
464-569 aa · 106 aa · 18.4% of protein
Raw token
HATPase_c:464:0.00000615:569:109:109- Raw architecture: HAMP:278:0.000000267:346:69:69#His_kinase:363:8.59e-19:435:73:80#HATPase_c:464:0.00000615:569:109:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466465::NZ_KE992660.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span34795-38095Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_00358RefSeq proteinWP_021634351.1
Context group ID
GCF_000466465::NZ_KE992660.1::G00031Context members
HMPREF1548_RS03425HMPREF1548_RS03430
Partner locus tags
HMPREF1548_RS03425HMPREF1548_RS03430
Partner old locus tags
HMPREF1548_00358HMPREF1548_00359
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021634351.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS03425Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_00358Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992660.1Sequence record reported by the local genomic context database.
Genomic interval34 795-36 528 nt1 734 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span34 795-38 095 ntGCF_000466465::NZ_KE992660.1::G00031
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992660.1::G00031Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992660.1All displayed genes belong to this local TCS context.
Neighborhood span34 795-38 095 nt3 301 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
34 795 nt38 095 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1548_RS03425GCF_000466465#HMPREF1548_RS03425
HKClassicCurrent focus
34 795-36 528 nt · Forward (+)
HMPREF1548_RS03430GCF_000466465#HMPREF1548_RS03430
RRunclassified
36 506-38 095 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS03425The current gene is the representative for this cluster.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.
PFAM architecture for HKOC_1177524
Simplified PFAM architecture for HKOC_1177524
PFAM domain coverage: 76 / 577 aa (13.2%)
1 aa577 aa
His_kinase
- Simplified architecture: His_kinase
- Raw architecture: His_kinase[363-438]
- Domain count: 1
- Matched identifier: HKOC_1177524
- Positioned domains: His_kinase 363-438
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS03425
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key