1 HAMP#1
181-250 aa · 70 aa · 14.2% of protein
Raw token
HAMP:181:0.000000000000873:250:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS02890
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength494 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466465#HMPREF1548_RS02890Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length494 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage252 / 494 aa (51.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa494 aa
Domain-by-domain annotation3 items
2 HisKA#2
261-328 aa · 68 aa · 13.8% of protein
Raw token
HisKA:261:0.0000000000000015:328:68:643 HATPase_c#3
375-488 aa · 114 aa · 23.1% of protein
Raw token
HATPase_c:375:1.11e-29:488:114:109- Raw architecture: HAMP:181:0.000000000000873:250:70:69#HisKA:261:0.0000000000000015:328:68:64#HATPase_c:375:1.11e-29:488:114:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466465::NZ_KE992657.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16917-19083Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_00231RefSeq proteinWP_021634224.1
Context group ID
GCF_000466465::NZ_KE992657.1::G00026Context members
HMPREF1548_RS02885HMPREF1548_RS02890
Partner locus tags
HMPREF1548_RS02885HMPREF1548_RS02890
Partner old locus tags
HMPREF1548_00230HMPREF1548_00231
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021634224.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS02890Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_00231Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992657.1Sequence record reported by the local genomic context database.
Genomic interval17 599-19 083 nt1 485 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span16 917-19 083 ntGCF_000466465::NZ_KE992657.1::G00026
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992657.1::G00026Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992657.1All displayed genes belong to this local TCS context.
Neighborhood span16 917-19 083 nt2 167 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 917 nt19 083 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1548_RS02885GCF_000466465#HMPREF1548_RS02885
RROmpR
16 917-17 606 nt · Reverse (-)
HMPREF1548_RS02890GCF_000466465#HMPREF1548_RS02890
HKClassicCurrent focus
17 599-19 083 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS02890The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1509790
Simplified PFAM architecture for HKOC_1509790
PFAM domain coverage: 229 / 494 aa (46.4%)
1 aa494 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[198-250] | HisKA[262-327] | HATPase_c[376-485]
- Domain count: 3
- Matched identifier: HKOC_1509790
- Positioned domains: HAMP 198-250 ; HisKA 262-327 ; HATPase_c 376-485
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS02890
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key