Gene detail

HMPREF1548_RS02720

Histidine kinase, Classic

Clostridium sp. KLE 1755 · GCF_000466465

ClassHKTypeClassicLength586 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000466465#HMPREF1548_RS02720Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1131489Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_021634184.1 · A0A3E3IN83 · MIST4 HMPREF1548_RS02720RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length586 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage488 / 586 aa (83.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa586 aa
dCache_1: 42-278 aa (237 aa)1HAMP: 295-359 aa (65 aa)2His_kinase: 379-458 aa (80 aa)3HATPase_c: 474-579 aa (106 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
42-278 aa · 237 aa · 40.4% of protein
Raw tokendCache_1:42:0.000000000602:278:243:195
2 HAMP#2
295-359 aa · 65 aa · 11.1% of protein
Raw tokenHAMP:295:0.000000000097:359:65:69
3 His_kinase#3
379-458 aa · 80 aa · 13.7% of protein
Raw tokenHis_kinase:379:7.89e-33:458:80:80
4 HATPase_c#4
474-579 aa · 106 aa · 18.1% of protein
Raw tokenHATPase_c:474:0.00000000000174:579:112:109
  • Raw architecture: dCache_1:42:0.000000000602:278:243:195#HAMP:295:0.000000000097:359:65:69#His_kinase:379:7.89e-33:458:80:80#HATPase_c:474:0.00000000000174:579:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000466465::NZ_KE992656.1::G00025
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span71445-73205Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_02169RefSeq proteinWP_021634184.1
Context group IDGCF_000466465::NZ_KE992656.1::G00025
Context members
HMPREF1548_RS02720
Partner locus tags
HMPREF1548_RS02720
Partner old locus tags
HMPREF1548_02169
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021634184.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E3IN83Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E3IN83_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1548_RS02720Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_02169Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992656.1Sequence record reported by the local genomic context database.
Genomic interval71 445-73 205 nt1 761 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span71 445-73 205 ntGCF_000466465::NZ_KE992656.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000466465::NZ_KE992656.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992656.1All displayed genes belong to this local TCS context.
Neighborhood span71 445-73 205 nt1 761 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
71 445 nt73 205 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1131489Run 6 · HK · 2 sequences
Representative sequenceGCF_000466465#HMPREF1548_RS02720The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1131489

Simplified PFAM architecture for HKOC_1131489

PFAM domain coverage: 227 / 586 aa (38.7%)

1 aa586 aa
HAMP: 316-359 aaHAMPHis_kinase: 379-457 aaHis_kinaseHATPase_c: 474-577 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[316-359] | His_kinase[379-457] | HATPase_c[474-577]
  • Domain count: 3
  • Matched identifier: HKOC_1131489
  • Positioned domains: HAMP 316-359 ; His_kinase 379-457 ; HATPase_c 474-577
Cluster members and taxonomy
Visualization

Representative gene: GCF_000466465#HMPREF1548_RS02720

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key