1 Hpt#1
10-77 aa · 68 aa · 9.4% of protein
Raw token
Hpt:10:0.000000000000801:77:68:84P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS02675
Histidine kinase, CheA
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeCheALength724 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466465#HMPREF1548_RS02675Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HptH-kinase_dimHATPase_cCheW
Protein length724 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage397 / 724 aa (54.8%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa724 aa
Domain-by-domain annotation4 items
2 H-kinase_dim#2
322-378 aa · 57 aa · 7.9% of protein
Raw token
H-kinase_dim:322:0.0000256:378:64:673 HATPase_c#3
424-563 aa · 140 aa · 19.3% of protein
Raw token
HATPase_c:424:4.65e-18:563:140:1094 CheW#4
569-700 aa · 132 aa · 18.2% of protein
Raw token
CheW:569:2.16e-16:700:138:138- Raw architecture: Hpt:10:0.000000000000801:77:68:84#H-kinase_dim:322:0.0000256:378:64:67#HATPase_c:424:4.65e-18:563:140:109#CheW:569:2.16e-16:700:138:138
- Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466465::NZ_KE992656.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span60202-63330Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_02157RefSeq proteinWP_021634172.1
Context group ID
GCF_000466465::NZ_KE992656.1::G00023Context members
HMPREF1548_RS02670HMPREF1548_RS02675
Partner locus tags
HMPREF1548_RS02670HMPREF1548_RS02675
Partner old locus tags
HMPREF1548_02156HMPREF1548_02157
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021634172.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E3IN73Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E3IN73_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS02675Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_02157Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992656.1Sequence record reported by the local genomic context database.
Genomic interval61 156-63 330 nt2 175 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span60 202-63 330 ntGCF_000466465::NZ_KE992656.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992656.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992656.1All displayed genes belong to this local TCS context.
Neighborhood span60 202-63 330 nt3 129 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
60 202 nt63 330 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1548_RS02670GCF_000466465#HMPREF1548_RS02670
RRPleD
60 202-61 140 nt · Forward (+)
HMPREF1548_RS02675GCF_000466465#HMPREF1548_RS02675
HKCheACurrent focus
61 156-63 330 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS02675The current gene is the representative for this cluster.
PFAM architectureHpt + P2 + HATPase_c + CheW4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0724619
Simplified PFAM architecture for HKOC_0724619
PFAM domain coverage: 421 / 724 aa (58.1%)
1 aa724 aa
HptP2HATPase_cCheW
- Simplified architecture: Hpt + P2 + HATPase_c + CheW
- Raw architecture: Hpt[10-83] | P2[189-265] | HATPase_c[426-564] | CheW[570-700]
- Domain count: 4
- Matched identifier: HKOC_0724619
- Positioned domains: Hpt 10-83 ; P2 189-265 ; HATPase_c 426-564 ; CheW 570-700
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS02675
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key