1 HAMP#1
296-364 aa · 69 aa · 11.4% of protein
Raw token
HAMP:296:0.00000532:364:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS01975
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength607 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000466465#HMPREF1548_RS01975Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length607 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage262 / 607 aa (43.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa607 aa
Domain-by-domain annotation3 items
2 His_kinase#2
386-466 aa · 81 aa · 13.3% of protein
Raw token
His_kinase:386:2.54e-29:466:81:803 HATPase_c#3
485-596 aa · 112 aa · 18.5% of protein
Raw token
HATPase_c:485:0.00000000000000325:596:114:109- Raw architecture: HAMP:296:0.00000532:364:69:69#His_kinase:386:2.54e-29:466:81:80#HATPase_c:485:0.00000000000000325:596:114:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000466465::NZ_KE992653.1::G00014
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span7063-8886Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_00181RefSeq proteinWP_021634003.1
Context group ID
GCF_000466465::NZ_KE992653.1::G00014Context members
HMPREF1548_RS01975
Partner locus tags
HMPREF1548_RS01975
Partner old locus tags
HMPREF1548_00181
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021634003.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS01975Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_00181Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992653.1Sequence record reported by the local genomic context database.
Genomic interval7 063-8 886 nt1 824 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span7 063-8 886 ntGCF_000466465::NZ_KE992653.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992653.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992653.1All displayed genes belong to this local TCS context.
Neighborhood span7 063-8 886 nt1 824 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 063 nt8 886 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF1548_RS01975GCF_000466465#HMPREF1548_RS01975
HKClassicCurrent focus
7 063-8 886 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS01975The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1018903
Simplified PFAM architecture for HKOC_1018903
PFAM domain coverage: 189 / 607 aa (31.1%)
1 aa607 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[386-466] | HATPase_c[487-594]
- Domain count: 2
- Matched identifier: HKOC_1018903
- Positioned domains: His_kinase 386-466 ; HATPase_c 487-594
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS01975
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key