1 HAMP#1
296-365 aa · 70 aa · 12.0% of protein
Raw token
HAMP:296:0.0000000843:365:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS01235
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength584 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466465#HMPREF1548_RS01235Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length584 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 584 aa (43.0%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa584 aa
Domain-by-domain annotation3 items
2 His_kinase#2
383-462 aa · 80 aa · 13.7% of protein
Raw token
His_kinase:383:1.71e-25:462:80:803 HATPase_c#3
480-580 aa · 101 aa · 17.3% of protein
Raw token
HATPase_c:480:0.000000615:580:107:109- Raw architecture: HAMP:296:0.0000000843:365:70:69#His_kinase:383:1.71e-25:462:80:80#HATPase_c:480:0.000000615:580:107:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466465::NZ_KE992649.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span23919-27327Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_00135RefSeq proteinWP_021633831.1
Context group ID
GCF_000466465::NZ_KE992649.1::G00005Context members
HMPREF1548_RS01235HMPREF1548_RS01240
Partner locus tags
HMPREF1548_RS01235HMPREF1548_RS01240
Partner old locus tags
HMPREF1548_00135HMPREF1548_00136
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021633831.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E3HW21Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E3HW21_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS01235Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_00135Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992649.1Sequence record reported by the local genomic context database.
Genomic interval23 919-25 673 nt1 755 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span23 919-27 327 ntGCF_000466465::NZ_KE992649.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992649.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992649.1All displayed genes belong to this local TCS context.
Neighborhood span23 919-27 327 nt3 409 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 919 nt27 327 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1548_RS01235GCF_000466465#HMPREF1548_RS01235
HKClassicCurrent focus
23 919-25 673 nt · Reverse (-)
HMPREF1548_RS01240GCF_000466465#HMPREF1548_RS01240
RRunclassified
25 663-27 327 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS01235The current gene is the representative for this cluster.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.
PFAM architecture for HKOC_1142151
Simplified PFAM architecture for HKOC_1142151
PFAM domain coverage: 80 / 584 aa (13.7%)
1 aa584 aa
His_kinase
- Simplified architecture: His_kinase
- Raw architecture: His_kinase[383-462]
- Domain count: 1
- Matched identifier: HKOC_1142151
- Positioned domains: His_kinase 383-462
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS01235
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key