Gene detail

QCW_RS02380

Histidine kinase, Hybrid

Clostridioides difficile CD69 · GCF_000449185

ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449185#QCW_RS02380Stable P2CS identifier used across views.
GenomeGCF_000449185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0484795Run 6 · 21 sequences · id 100% · cov 80% · representative
External referencesWP_021374443.1 · MIST4 QCW_RS02380RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 852 aa (48.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCW_RS02380
Domain-by-domain annotation4 items
1 HisKA#1
344-410 aa · 67 aa · 7.9% of protein
Raw tokenHisKA:344:7.21e-18:410:67:64
2 HATPase_c#2
458-576 aa · 119 aa · 14.0% of protein
Raw tokenHATPase_c:458:5.23e-25:576:120:109
3 Response_reg#3
592-696 aa · 105 aa · 12.3% of protein
Raw tokenResponse_reg:592:3.14e-22:696:105:111
4 Response_reg#4
731-848 aa · 118 aa · 13.8% of protein
Raw tokenResponse_reg:731:5.43e-27:848:118:111
  • Raw architecture: HisKA:344:7.21e-18:410:67:64#HATPase_c:458:5.23e-25:576:120:109#Response_reg:592:3.14e-22:696:105:111#Response_reg:731:5.43e-27:848:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449185::NZ_AVHE01000013.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span78435-83003Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCW_0478RefSeq proteinWP_021374443.1
Context group IDGCF_000449185::NZ_AVHE01000013.1::G00002
Context members
QCW_RS02380QCW_RS02390
Partner locus tags
QCW_RS02380QCW_RS02390
Partner old locus tags
QCW_0478QCW_0480
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021374443.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCW_RS02380Primary locus identifier stored in the genes table.
Old locus tagQCW_0478Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHE01000013.1Sequence record reported by the local genomic context database.
Genomic interval78 435-80 993 nt2 559 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span78 435-83 003 ntGCF_000449185::NZ_AVHE01000013.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449185::NZ_AVHE01000013.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHE01000013.1All displayed genes belong to this local TCS context.
Neighborhood span78 435-83 003 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
78 435 nt83 003 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCW_RS02380GCF_000449185#QCW_RS02380
HKHybridCurrent focus

78 435-80 993 nt · Reverse (-)

Old locus QCW_0478RefSeq WP_021374443.1
QCW_RS02390GCF_000449185#QCW_RS02390
RRRpfG

81 363-83 003 nt · Reverse (-)

Old locus QCW_0480RefSeq WP_021394725.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484795Run 6 · HK · 21 sequences
Representative sequenceGCF_000449185#QCW_RS02380The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484795

Simplified PFAM architecture for HKOC_0484795

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0484795
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS02380

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 21 over 21 total members. Page 1 / 1.

GCF_000449185#QCW_RS02380 (representative)
QCW_RS02380 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_001704805#DCP99_RS11935
DCP99_RS11935 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_002165155#DCQ05_RS14580
DCQ05_RS14580 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_003456975#CDIF102859_RS03175
CDIF102859_RS03175 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_003457015#CDIF102860_RS03620
CDIF102860_RS03620 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_003457035#CDIF102978_RS03620
CDIF102978_RS03620 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_004314745#E0O51_RS10770
E0O51_RS10770 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_004315765#E0P52_RS04830
E0P52_RS04830 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_005786645#EDC95_RS12875
EDC95_RS12875 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_012030175#GSQ43_RS01635
GSQ43_RS01635 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_019426665#K1N14_RS03850
K1N14_RS03850 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_024260215#NMF84_RS07495
NMF84_RS07495 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_028597315#PSM44_RS13110
PSM44_RS13110 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_033840445#SIK48_RS05925
SIK48_RS05925 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_038754145#ABCP49_RS06515
ABCP49_RS06515 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_038755145#ABCR36_RS06840
ABCR36_RS06840 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_900165935#B2B89_RS09115
B2B89_RS09115 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_900165975#B2A22_RS05475
B2A22_RS05475 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_900166005#B2A70_RS06470
B2A70_RS06470 · HK · Hybrid
RefSeq: WP_330394115.1
GCF_900166015#B2C46_RS05185
B2C46_RS05185 · HK · Hybrid
RefSeq: WP_021374443.1
GCF_901004505#FJF26_RS05315
FJF26_RS05315 · HK · Hybrid
RefSeq: WP_021374443.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 274 · GCF_000449185
AssemblyASM44918v2 · Contighaploid
Genome composition3 991 067 bp · 28,5% GCClostridioides difficile CD69
Signal transduction countsGenes 95 · HK 43 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key