Gene detail

B2A70_RS06470

Histidine kinase, Hybrid

Clostridioides difficile · GCF_900166005

ClassHKTypeHybridLength801 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_900166005#B2A70_RS06470Stable P2CS identifier used across views.
GenomeGCF_900166005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0484795Run 6 · 21 sequences · id 100% · cov 80%
External referencesWP_330394115.1 · MIST4 B2A70_RS06470RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length801 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 801 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B2A70_RS06470
Domain-by-domain annotation4 items
1 HisKA#1
293-359 aa · 67 aa · 8.4% of protein
Raw tokenHisKA:293:7.96e-18:359:67:64
2 HATPase_c#2
407-525 aa · 119 aa · 14.9% of protein
Raw tokenHATPase_c:407:4.66e-25:525:120:109
3 Response_reg#3
541-645 aa · 105 aa · 13.1% of protein
Raw tokenResponse_reg:541:4.56e-22:645:105:111
4 Response_reg#4
680-797 aa · 118 aa · 14.7% of protein
Raw tokenResponse_reg:680:8.59e-27:797:118:111
  • Raw architecture: HisKA:293:7.96e-18:359:67:64#HATPase_c:407:4.66e-25:525:120:109#Response_reg:541:4.56e-22:645:105:111#Response_reg:680:8.59e-27:797:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_900166005::NZ_FUST01000006.1::G00023
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span15255-17660Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239411_01315RefSeq proteinWP_330394115.1
Context group IDGCF_900166005::NZ_FUST01000006.1::G00023
Context members
B2A70_RS06470
Partner locus tags
B2A70_RS06470
Partner old locus tags
SAMEA2239411_01315
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330394115.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2A70_RS06470Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239411_01315Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUST01000006.1Sequence record reported by the local genomic context database.
Genomic interval15 255-17 660 nt2 406 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 255-17 660 ntGCF_900166005::NZ_FUST01000006.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900166005::NZ_FUST01000006.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUST01000006.1All displayed genes belong to this local TCS context.
Neighborhood span15 255-17 660 nt2 406 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 255 nt17 660 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

B2A70_RS06470GCF_900166005#B2A70_RS06470
HKHybridCurrent focus

15 255-17 660 nt · Forward (+)

Old locus SAMEA2239411_01315RefSeq WP_330394115.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484795Run 6 · HK · 21 sequences
Representative sequenceGCF_000449185#QCW_RS02380Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484795

Simplified PFAM architecture for HKOC_0484795

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0484795
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS02380

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900166005
Assembly11670_1#63 · Scaffoldhaploid
Genome composition4 122 619 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key