1 HisKA#1
344-410 aa · 67 aa · 7.9% of protein
Raw token
HisKA:344:7.21e-18:410:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK48_RS05925
Histidine kinase, Hybrid
Clostridioides difficile · GCF_033840445
ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_033840445#SIK48_RS05925Stable P2CS identifier used across views.
GenomeGCF_033840445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 852 aa (48.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation4 items
2 HATPase_c#2
458-576 aa · 119 aa · 14.0% of protein
Raw token
HATPase_c:458:5.23e-25:576:120:1093 Response_reg#3
592-696 aa · 105 aa · 12.3% of protein
Raw token
Response_reg:592:3.14e-22:696:105:1114 Response_reg#4
731-848 aa · 118 aa · 13.8% of protein
Raw token
Response_reg:731:5.43e-27:848:118:111- Raw architecture: HisKA:344:7.21e-18:410:67:64#HATPase_c:458:5.23e-25:576:120:109#Response_reg:592:3.14e-22:696:105:111#Response_reg:731:5.43e-27:848:118:111
- Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_033840445::NZ_JAWXRM010000028.1::G00024
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13145-17713Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK48_05935RefSeq proteinWP_021374443.1
Context group ID
GCF_033840445::NZ_JAWXRM010000028.1::G00024Context members
SIK48_RS05915SIK48_RS05925
Partner locus tags
SIK48_RS05915SIK48_RS05925
Partner old locus tags
SIK48_05925SIK48_05935
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021374443.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK48_RS05925Primary locus identifier stored in the genes table.
Old locus tagSIK48_05935Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRM010000028.1Sequence record reported by the local genomic context database.
Genomic interval15 155-17 713 nt2 559 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span13 145-17 713 ntGCF_033840445::NZ_JAWXRM010000028.1::G00024
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033840445::NZ_JAWXRM010000028.1::G00024Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRM010000028.1All displayed genes belong to this local TCS context.
Neighborhood span13 145-17 713 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 145 nt17 713 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SIK48_RS05915GCF_033840445#SIK48_RS05915
RRRpfG
13 145-14 785 nt · Forward (+)
SIK48_RS05925GCF_033840445#SIK48_RS05925
HKHybridCurrent focus
15 155-17 713 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449185#QCW_RS02380Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0484795
Simplified PFAM architecture for HKOC_0484795
PFAM domain coverage: 413 / 852 aa (48.5%)
1 aa852 aa
HisKAHATPase_cResponse_regResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
- Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
- Domain count: 4
- Matched identifier: HKOC_0484795
- Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Representative gene: GCF_000449185#QCW_RS02380
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840445
AssemblyASM3384044v1 · Contighaploid
Genome composition3 979 416 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 90 · HK 42 · RR 47CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key