Gene detail

HMPREF1093_RS09535

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength473 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS09535Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1687196Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_002601711.1 · A0A6N3BXI6 · MIST4 HMPREF1093_RS09535RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NPAS_4HisKA_2HATPase_c
Protein length473 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage377 / 473 aa (79.7%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 PAS_4,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa473 aa
H_kinase_N: 19-137 aa (119 aa)1PAS_4: 169-264 aa (96 aa)2HisKA_2: 282-356 aa (75 aa)3HATPase_c: 385-471 aa (87 aa)4
Domain-by-domain annotation4 items
1 H_kinase_N#1
19-137 aa · 119 aa · 25.2% of protein
Raw tokenH_kinase_N:19:3.57e-16:137:122:139
2 PAS_4#2
169-264 aa · 96 aa · 20.3% of protein
Raw tokenPAS_4:169:0.000000912:264:107:110
3 HisKA_2#3
282-356 aa · 75 aa · 15.9% of protein
Raw tokenHisKA_2:282:0.00000000000000633:356:76:76
4 HATPase_c#4
385-471 aa · 87 aa · 18.4% of protein
Raw tokenHATPase_c:385:0.0000000000000084:471:102:109
  • Raw architecture: H_kinase_N:19:3.57e-16:137:122:139#PAS_4:169:0.000000912:264:107:110#HisKA_2:282:0.00000000000000633:356:76:76#HATPase_c:385:0.0000000000000084:471:102:109
  • Domain description: 1 H_kinase_N,1 PAS_4,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850950.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2262800-2264869Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_01915RefSeq proteinWP_002601711.1
Context group IDGCF_000371445::NZ_KB850950.1::G00052
Context members
HMPREF1093_RS09535HMPREF1093_RS09540
Partner locus tags
HMPREF1093_RS09535HMPREF1093_RS09540
Partner old locus tags
HMPREF1093_01915HMPREF1093_01916
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002601711.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3BXI6Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3BXI6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS09535Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_01915Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850950.1Sequence record reported by the local genomic context database.
Genomic interval2 262 800-2 264 221 nt1 422 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 262 800-2 264 869 ntGCF_000371445::NZ_KB850950.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850950.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850950.1All displayed genes belong to this local TCS context.
Neighborhood span2 262 800-2 264 869 nt2 070 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 262 800 nt2 264 869 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS09535GCF_000371445#HMPREF1093_RS09535
HKClassicCurrent focus

2 262 800-2 264 221 nt · Reverse (-)

Old locus HMPREF1093_01915RefSeq WP_002601711.1
HMPREF1093_RS09540GCF_000371445#HMPREF1093_RS09540
RRAmiR_NasR

2 264 294-2 264 869 nt · Reverse (-)

Old locus HMPREF1093_01916RefSeq WP_002601712.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1687196Run 6 · HK · 5 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS09535The current gene is the representative for this cluster.
PFAM architectureGAF_PdtaS + PAS_8 + HisKA_2 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1687196

Simplified PFAM architecture for HKOC_1687196

PFAM domain coverage: 340 / 473 aa (71.9%)

1 aa473 aa
GAF_PdtaS: 15-138 aaGAF_PdtaSPAS_8: 163-215 aaPAS_8HisKA_2: 282-354 aaHisKA_2HATPase_c: 381-470 aaHATPase_c
GAF_PdtaSPAS_8HisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + PAS_8 + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[15-138] | PAS_8[163-215] | HisKA_2[282-354] | HATPase_c[381-470]
  • Domain count: 4
  • Matched identifier: HKOC_1687196
  • Positioned domains: GAF_PdtaS 15-138 ; PAS_8 163-215 ; HisKA_2 282-354 ; HATPase_c 381-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS09535

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key