Gene detail

HMPREF1093_RS04400

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength557 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS04400Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1268419Run 6 · 9 sequences · id 100% · cov 80% · representative
External referencesWP_002600698.1 · A0A2V3YR57 · MIST4 HMPREF1093_RS04400RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length557 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage233 / 557 aa (41.8%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa557 aa
HAMP: 274-339 aa (66 aa)1His_kinase: 356-428 aa (73 aa)2HATPase_c: 458-551 aa (94 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
274-339 aa · 66 aa · 11.8% of protein
Raw tokenHAMP:274:0.0000000000207:339:66:69
2 His_kinase#2
356-428 aa · 73 aa · 13.1% of protein
Raw tokenHis_kinase:356:3.04e-21:428:73:80
3 HATPase_c#3
458-551 aa · 94 aa · 16.9% of protein
Raw tokenHATPase_c:458:0.000000162:551:98:109
  • Raw architecture: HAMP:274:0.0000000000207:339:66:69#His_kinase:356:3.04e-21:428:73:80#HATPase_c:458:0.000000162:551:98:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850950.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1012328-1015593Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_00887RefSeq proteinWP_002600698.1
Context group IDGCF_000371445::NZ_KB850950.1::G00028
Context members
HMPREF1093_RS04395HMPREF1093_RS04400
Partner locus tags
HMPREF1093_RS04395HMPREF1093_RS04400
Partner old locus tags
HMPREF1093_00886HMPREF1093_00887
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002600698.1Primary protein accession used for annex mappings.
UniProt accessionA0A2V3YR57Primary UniProt accession resolved in the annex database.
UniProt IDA0A2V3YR57_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS04400Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_00887Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850950.1Sequence record reported by the local genomic context database.
Genomic interval1 013 920-1 015 593 nt1 674 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 012 328-1 015 593 ntGCF_000371445::NZ_KB850950.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850950.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850950.1All displayed genes belong to this local TCS context.
Neighborhood span1 012 328-1 015 593 nt3 266 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 012 328 nt1 015 593 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS04395GCF_000371445#HMPREF1093_RS04395
RRunclassified

1 012 328-1 013 905 nt · Reverse (-)

Old locus HMPREF1093_00886RefSeq WP_002600697.1
HMPREF1093_RS04400GCF_000371445#HMPREF1093_RS04400
HKClassicCurrent focus

1 013 920-1 015 593 nt · Reverse (-)

Old locus HMPREF1093_00887RefSeq WP_002600698.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1268419Run 6 · HK · 9 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS04400The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1268419

Simplified PFAM architecture for HKOC_1268419

PFAM domain coverage: 214 / 557 aa (38.4%)

1 aa557 aa
HAMP: 294-339 aaHAMPHis_kinase: 356-428 aaHis_kinaseHATPase_c: 458-552 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[294-339] | His_kinase[356-428] | HATPase_c[458-552]
  • Domain count: 3
  • Matched identifier: HKOC_1268419
  • Positioned domains: HAMP 294-339 ; His_kinase 356-428 ; HATPase_c 458-552
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS04400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key