Gene detail

HMPREF1093_RS00325

Histidine kinase, Hybrid

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeHybridLength893 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000371445#HMPREF1093_RS00325Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_0424073Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_002599877.1 · MIST4 HMPREF1093_RS00325RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3PAS_9HisKAHATPase_cResponse_reg
Protein length893 aaLength used to scale native and Biotite-like views.
Annotated domains77 with usable coordinates.
Domain coverage645 / 893 aa (72.2%)Merged over positioned domains only.
Domain description2 PAS_3,1 PAS_9,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa893 aa
PAS_3: 11-96 aa (86 aa)1PAS_9: 132-207 aa (76 aa)2PAS_3: 262-341 aa (80 aa)3HisKA: 382-448 aa (67 aa)4HATPase_c: 495-607 aa (113 aa)5Response_reg: 629-734 aa (106 aa)6Response_reg: 773-889 aa (117 aa)7
Domain-by-domain annotation7 items
1 PAS_3#1
11-96 aa · 86 aa · 9.6% of protein
Raw tokenPAS_3:11:0.000000000995:96:86:89
2 PAS_9#2
132-207 aa · 76 aa · 8.5% of protein
Raw tokenPAS_9:132:0.0000259:207:77:102
3 PAS_3#3
262-341 aa · 80 aa · 9.0% of protein
Raw tokenPAS_3:262:0.00000324:341:80:89
4 HisKA#4
382-448 aa · 67 aa · 7.5% of protein
Raw tokenHisKA:382:5.47e-17:448:67:64
5 HATPase_c#5
495-607 aa · 113 aa · 12.7% of protein
Raw tokenHATPase_c:495:7.35e-29:607:113:109
6 Response_reg#6
629-734 aa · 106 aa · 11.9% of protein
Raw tokenResponse_reg:629:8.3e-24:734:108:111
7 Response_reg#7
773-889 aa · 117 aa · 13.1% of protein
Raw tokenResponse_reg:773:1.82e-26:889:117:111
  • Raw architecture: PAS_3:11:0.000000000995:96:86:89#PAS_9:132:0.0000259:207:77:102#PAS_3:262:0.00000324:341:80:89#HisKA:382:5.47e-17:448:67:64#HATPase_c:495:7.35e-29:607:113:109#Response_reg:629:8.3e-24:734:108:111#Response_reg:773:1.82e-26:889:117:111
  • Domain description: 2 PAS_3,1 PAS_9,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000371445::NZ_KB850950.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span76292-79000Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_00063RefSeq proteinWP_002599877.1
Context group IDGCF_000371445::NZ_KB850950.1::G00004
Context members
HMPREF1093_RS00325
Partner locus tags
HMPREF1093_RS00325
Partner old locus tags
HMPREF1093_00063
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002599877.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS00325Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_00063Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850950.1Sequence record reported by the local genomic context database.
Genomic interval76 292-79 000 nt2 709 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span76 292-79 000 ntGCF_000371445::NZ_KB850950.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850950.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850950.1All displayed genes belong to this local TCS context.
Neighborhood span76 292-79 000 nt2 709 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
76 292 nt79 000 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0424073Run 6 · HK · 1 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS00325The current gene is the representative for this cluster.
PFAM architecturePAS_3 + PAS_9 + HisKA + HATPase_c + Response_reg + Response_reg6 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0424073

Simplified PFAM architecture for HKOC_0424073

PFAM domain coverage: 537 / 893 aa (60.1%)

1 aa893 aa
PAS_3: 11-87 aaPAS_3PAS_9: 133-181 aaPAS_9HisKA: 382-448 aaHisKAHATPase_c: 496-609 aaHATPase_cResponse_reg: 629-742 aaResponse_regResponse_reg: 773-888 aaResponse_reg
PAS_3PAS_9HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + PAS_9 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[11-87] | PAS_9[133-181] | HisKA[382-448] | HATPase_c[496-609] | Response_reg[629-742] | Response_reg[773-888]
  • Domain count: 6
  • Matched identifier: HKOC_0424073
  • Positioned domains: PAS_3 11-87 ; PAS_9 133-181 ; HisKA 382-448 ; HATPase_c 496-609 ; Response_reg 629-742 ; Response_reg 773-888
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS00325

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key