1 HAMP#1
155-224 aa · 70 aa · 15.6% of protein
Raw token
HAMP:155:0.000000000702:224:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECBCE002MS12_RS0124770
Histidine kinase, Classic
Escherichia coli BCE002_MS12 · GCF_000354295
ClassHKTypeClassicLength448 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000354295#ECBCE002MS12_RS0124770Stable P2CS identifier used across views.
GenomeGCF_000354295Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length448 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 448 aa (54.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa448 aa
Domain-by-domain annotation3 items
2 HisKA#2
229-295 aa · 67 aa · 15.0% of protein
Raw token
HisKA:229:0.00000000000345:295:67:643 HATPase_c#3
338-445 aa · 108 aa · 24.1% of protein
Raw token
HATPase_c:338:9.31e-24:445:111:109- Raw architecture: HAMP:155:0.000000000702:224:70:69#HisKA:229:0.00000000000345:295:67:64#HATPase_c:338:9.31e-24:445:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000354295::NZ_AQDA01000081.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span164183-166260Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECBCE002MS12_3682RefSeq proteinWP_014641165.1
Context group ID
GCF_000354295::NZ_AQDA01000081.1::G00029Context members
ECBCE002MS12_RS0124770ECBCE002MS12_RS05080
Partner locus tags
ECBCE002MS12_RS0124770ECBCE002MS12_RS05080
Partner old locus tags
ECBCE002MS12_3682ECBCE002MS12_3683
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_014641165.1Primary protein accession used for annex mappings.
UniProt accessionK7QUL1Primary UniProt accession resolved in the annex database.
UniProt IDK7QUL1_KLEPNDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECBCE002MS12_RS0124770Primary locus identifier stored in the genes table.
Old locus tagECBCE002MS12_3682Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AQDA01000081.1Sequence record reported by the local genomic context database.
Genomic interval164 183-165 529 nt1 347 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span164 183-166 260 ntGCF_000354295::NZ_AQDA01000081.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000354295::NZ_AQDA01000081.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AQDA01000081.1All displayed genes belong to this local TCS context.
Neighborhood span164 183-166 260 nt2 078 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
164 183 nt166 260 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECBCE002MS12_RS0124770GCF_000354295#ECBCE002MS12_RS0124770
HKClassicCurrent focus
164 183-165 529 nt · Reverse (-)
ECBCE002MS12_RS05080GCF_000354295#ECBCE002MS12_RS05080
RROmpR
165 562-166 260 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_009822355#FHE88_RS17635Use this link to inspect the representative gene detail.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1678658
Simplified PFAM architecture for HKOC_1678658
PFAM domain coverage: 388 / 474 aa (81.9%)
1 aa474 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[5-166] | HAMP[191-242] | HisKA[248-313] | HATPase_c[356-463]
- Domain count: 4
- Matched identifier: HKOC_1678658
- Positioned domains: CusS 5-166 ; HAMP 191-242 ; HisKA 248-313 ; HATPase_c 356-463
Cluster members and taxonomy
Representative gene: GCF_009822355#FHE88_RS17635
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 116 112 · GCF_000354295
AssemblyASM35429v1 · Contighaploid
Genome composition4 946 441 bp · 50,5% GCEscherichia coli BCE002_MS12
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key