Gene detail

ECBCE002MS12_RS01730

Histidine kinase, Classic

Escherichia coli BCE002_MS12 · GCF_000354295

ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000354295#ECBCE002MS12_RS01730Stable P2CS identifier used across views.
GenomeGCF_000354295Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2712010Run 6 · 120 sequences · id 100% · cov 80%
External referencesWP_001052134.1 · A0A7U9J0H0 · MIST4 ECBCE002MS12_RS01730RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
HAMP: 72-139 aa (68 aa)1HisKA: 147-204 aa (58 aa)2HATPase_c: 252-360 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw tokenHAMP:72:0.000000989:139:68:69
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw tokenHisKA:147:0.00000000202:204:61:64
3 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw tokenHATPase_c:252:1.13e-21:360:111:109
  • Raw architecture: HAMP:72:0.000000989:139:68:69#HisKA:147:0.00000000202:204:61:64#HATPase_c:252:1.13e-21:360:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000354295::NZ_AQDA01000090.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span113853-115622Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECBCE002MS12_4400RefSeq proteinWP_001052134.1
Context group IDGCF_000354295::NZ_AQDA01000090.1::G00035
Context members
ECBCE002MS12_RS01730ECBCE002MS12_RS01725
Partner locus tags
ECBCE002MS12_RS01730ECBCE002MS12_RS01725
Partner old locus tags
ECBCE002MS12_4400ECBCE002MS12_4401
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001052134.1Primary protein accession used for annex mappings.
UniProt accessionA0A7U9J0H0Primary UniProt accession resolved in the annex database.
UniProt IDA0A7U9J0H0_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECBCE002MS12_RS01730Primary locus identifier stored in the genes table.
Old locus tagECBCE002MS12_4400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AQDA01000090.1Sequence record reported by the local genomic context database.
Genomic interval113 853-114 953 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span113 853-115 622 ntGCF_000354295::NZ_AQDA01000090.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000354295::NZ_AQDA01000090.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AQDA01000090.1All displayed genes belong to this local TCS context.
Neighborhood span113 853-115 622 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
113 853 nt115 622 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECBCE002MS12_RS01725GCF_000354295#ECBCE002MS12_RS01725
RROmpR

114 954-115 622 nt · Reverse (-)

Old locus ECBCE002MS12_4401RefSeq WP_001455658.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2712010Run 6 · HK · 120 sequences
Representative sequenceGCF_000166555#TW10722_RS0120555Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2712010

Simplified PFAM architecture for HKOC_2712010

PFAM domain coverage: 165 / 366 aa (45.1%)

1 aa366 aa
HisKA: 147-203 aaHisKAHATPase_c: 252-359 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[147-203] | HATPase_c[252-359]
  • Domain count: 2
  • Matched identifier: HKOC_2712010
  • Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Visualization

Representative gene: GCF_000166555#TW10722_RS0120555

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 116 112 · GCF_000354295
AssemblyASM35429v1 · Contighaploid
Genome composition4 946 441 bp · 50,5% GCEscherichia coli BCE002_MS12
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key