Gene detail

C201_RS01385

Histidine kinase, Classic

Escherichia coli S17 · GCF_000340255

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000340255#C201_RS01385Stable P2CS identifier used across views.
GenomeGCF_000340255Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1674090Run 6 · 7846 sequences · id 100% · cov 80%
External referencesWP_001219614.1 · A0A8E0FJS5 · MIST4 C201_RS01385RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 474 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 184-251 aa (68 aa)1HisKA: 257-319 aa (63 aa)2HATPase_c: 365-469 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
184-251 aa · 68 aa · 14.3% of protein
Raw tokenHAMP:184:0.00000000025:251:68:69
2 HisKA#2
257-319 aa · 63 aa · 13.3% of protein
Raw tokenHisKA:257:0.0000000000006:319:63:64
3 HATPase_c#3
365-469 aa · 105 aa · 22.2% of protein
Raw tokenHATPase_c:365:9.32e-24:469:105:109
  • Raw architecture: HAMP:184:0.00000000025:251:68:69#HisKA:257:0.0000000000006:319:63:64#HATPase_c:365:9.32e-24:469:105:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000340255::NZ_AOGN01000136.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span20407-22520Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC201_21100RefSeq proteinWP_001219614.1
Context group IDGCF_000340255::NZ_AOGN01000136.1::G00035
Context members
C201_RS01390C201_RS01385
Partner locus tags
C201_RS01390C201_RS01385
Partner old locus tags
C201_21095C201_21100
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001219614.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0FJS5Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0FJS5_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC201_RS01385Primary locus identifier stored in the genes table.
Old locus tagC201_21100Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AOGN01000136.1Sequence record reported by the local genomic context database.
Genomic interval21 096-22 520 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span20 407-22 520 ntGCF_000340255::NZ_AOGN01000136.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000340255::NZ_AOGN01000136.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AOGN01000136.1All displayed genes belong to this local TCS context.
Neighborhood span20 407-22 520 nt2 114 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
20 407 nt22 520 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C201_RS01390GCF_000340255#C201_RS01390
RROmpR

20 407-21 096 nt · Forward (+)

Old locus C201_21095RefSeq WP_001188664.1
C201_RS01385GCF_000340255#C201_RS01385
HKClassicCurrent focus

21 096-22 520 nt · Forward (+)

Old locus C201_21100RefSeq WP_001219614.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674090Run 6 · HK · 7846 sequences
Representative sequenceGCF_000009565#B21_RS22575Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674090

Simplified PFAM architecture for HKOC_1674090

PFAM domain coverage: 217 / 474 aa (45.8%)

1 aa474 aa
HAMP: 202-251 aaHAMPHisKA: 258-319 aaHisKAHATPase_c: 365-469 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[202-251] | HisKA[258-319] | HATPase_c[365-469]
  • Domain count: 3
  • Matched identifier: HKOC_1674090
  • Positioned domains: HAMP 202-251 ; HisKA 258-319 ; HATPase_c 365-469
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009565#B21_RS22575

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 227 813 · GCF_000340255
AssemblyS17 · Contighaploid
Genome composition4 591 470 bp · 51,0% GCEscherichia coli S17
Signal transduction countsGenes 62 · HK 29 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key