Gene detail

EFS1_RS07545

Histidine kinase, Classic

Enterococcus faecalis str. Symbioflor 1 · GCF_000317915

ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000317915#EFS1_RS07545Stable P2CS identifier used across views.
GenomeGCF_000317915Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1105109Run 6 · 357 sequences · id 100% · cov 80%
External referencesWP_002381855.1 · MIST4 EFS1_RS07545RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likePAS_4HisKAHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage395 / 591 aa (66.8%)Merged over positioned domains only.
Domain description1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
sCache_like: 36-155 aa (120 aa)1PAS_4: 256-361 aa (106 aa)2HisKA: 365-428 aa (64 aa)3HATPase_c: 484-588 aa (105 aa)4
Domain-by-domain annotation4 items
1 sCache_like#1
36-155 aa · 120 aa · 20.3% of protein
Raw tokensCache_like:36:0.000000000286:155:121:114
2 PAS_4#2
256-361 aa · 106 aa · 17.9% of protein
Raw tokenPAS_4:256:0.00000000281:361:111:110
3 HisKA#3
365-428 aa · 64 aa · 10.8% of protein
Raw tokenHisKA:365:4.17e-16:428:64:64
4 HATPase_c#4
484-588 aa · 105 aa · 17.8% of protein
Raw tokenHATPase_c:484:1.12e-31:588:105:109
  • Raw architecture: sCache_like:36:0.000000000286:155:121:114#PAS_4:256:0.00000000281:361:111:110#HisKA:365:4.17e-16:428:64:64#HATPase_c:484:1.12e-31:588:105:109
  • Domain description: 1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000317915::NC_019770.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1504218-1506700Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFS1_1459RefSeq proteinWP_002381855.1
Context group IDGCF_000317915::NC_019770.1::G00009
Context members
EFS1_RS07540EFS1_RS07545
Partner locus tags
EFS1_RS07540EFS1_RS07545
Partner old locus tags
EFS1_1458EFS1_1459
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002381855.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFS1_RS07545Primary locus identifier stored in the genes table.
Old locus tagEFS1_1459Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_019770.1Sequence record reported by the local genomic context database.
Genomic interval1 504 925-1 506 700 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 504 218-1 506 700 ntGCF_000317915::NC_019770.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000317915::NC_019770.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_019770.1All displayed genes belong to this local TCS context.
Neighborhood span1 504 218-1 506 700 nt2 483 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 504 218 nt1 506 700 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFS1_RS07540GCF_000317915#EFS1_RS07540
RROmpR

1 504 218-1 504 928 nt · Forward (+)

Old locus EFS1_1458RefSeq WP_002364032.1
EFS1_RS07545GCF_000317915#EFS1_RS07545
HKClassicCurrent focus

1 504 925-1 506 700 nt · Forward (+)

Old locus EFS1_1459RefSeq WP_002381855.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1105109Run 6 · HK · 357 sequences
Representative sequenceGCF_000147515#HMPREF9503_RS09935Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1105109

Simplified PFAM architecture for HKOC_1105109

PFAM domain coverage: 276 / 591 aa (46.7%)

1 aa591 aa
PAS_4: 256-360 aaPAS_4HisKA: 366-429 aaHisKAHATPase_c: 481-587 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[256-360] | HisKA[366-429] | HATPase_c[481-587]
  • Domain count: 3
  • Matched identifier: HKOC_1105109
  • Positioned domains: PAS_4 256-360 ; HisKA 366-429 ; HATPase_c 481-587
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147515#HMPREF9503_RS09935

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 261 557 · GCF_000317915
AssemblyASM31791v1 · Complete Genomehaploid
Genome composition2 810 675 bp · 37,5% GCEnterococcus faecalis str. Symbioflor 1
Signal transduction countsGenes 30 · HK 14 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key