Gene detail

EFS1_RS04545

Histidine kinase, Classic

Enterococcus faecalis str. Symbioflor 1 · GCF_000317915

ClassHKTypeClassicLength502 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000317915#EFS1_RS04545Stable P2CS identifier used across views.
GenomeGCF_000317915Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1463908Run 6 · 145 sequences · id 100% · cov 80%
External referencesWP_002388912.1 · MIST4 EFS1_RS04545RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length502 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 502 aa (49.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa502 aa
HAMP: 195-266 aa (72 aa)1HisKA: 270-336 aa (67 aa)2HATPase_c: 384-493 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
195-266 aa · 72 aa · 14.3% of protein
Raw tokenHAMP:195:0.00000000000698:266:72:69
2 HisKA#2
270-336 aa · 67 aa · 13.3% of protein
Raw tokenHisKA:270:0.00000000000000835:336:67:64
3 HATPase_c#3
384-493 aa · 110 aa · 21.9% of protein
Raw tokenHATPase_c:384:1.06e-29:493:110:109
  • Raw architecture: HAMP:195:0.00000000000698:266:72:69#HisKA:270:0.00000000000000835:336:67:64#HATPase_c:384:1.06e-29:493:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000317915::NC_019770.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span902004-904209Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFS1_0879RefSeq proteinWP_002388912.1
Context group IDGCF_000317915::NC_019770.1::G00003
Context members
EFS1_RS04540EFS1_RS04545
Partner locus tags
EFS1_RS04540EFS1_RS04545
Partner old locus tags
EFS1_0878EFS1_0879
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002388912.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFS1_RS04545Primary locus identifier stored in the genes table.
Old locus tagEFS1_0879Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_019770.1Sequence record reported by the local genomic context database.
Genomic interval902 701-904 209 nt1 509 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span902 004-904 209 ntGCF_000317915::NC_019770.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000317915::NC_019770.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_019770.1All displayed genes belong to this local TCS context.
Neighborhood span902 004-904 209 nt2 206 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
902 004 nt904 209 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFS1_RS04540GCF_000317915#EFS1_RS04540
RROmpR

902 004-902 690 nt · Forward (+)

Old locus EFS1_0878RefSeq WP_002355954.1
EFS1_RS04545GCF_000317915#EFS1_RS04545
HKClassicCurrent focus

902 701-904 209 nt · Forward (+)

Old locus EFS1_0879RefSeq WP_002388912.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1463908Run 6 · HK · 145 sequences
Representative sequenceGCF_000148165#HMPREF9495_RS10910Use this link to inspect the representative gene detail.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1463908

Simplified PFAM architecture for HKOC_1463908

PFAM domain coverage: 372 / 502 aa (74.1%)

1 aa502 aa
ArlS_N: 45-189 aaArlS_NHAMP: 213-265 aaHAMPHisKA: 271-336 aaHisKAHATPase_c: 385-492 aaHATPase_c
ArlS_NHAMPHisKAHATPase_c
  • Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
  • Raw architecture: ArlS_N[45-189] | HAMP[213-265] | HisKA[271-336] | HATPase_c[385-492]
  • Domain count: 4
  • Matched identifier: HKOC_1463908
  • Positioned domains: ArlS_N 45-189 ; HAMP 213-265 ; HisKA 271-336 ; HATPase_c 385-492
Cluster members and taxonomy
Visualization

Representative gene: GCF_000148165#HMPREF9495_RS10910

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 261 557 · GCF_000317915
AssemblyASM31791v1 · Complete Genomehaploid
Genome composition2 810 675 bp · 37,5% GCEnterococcus faecalis str. Symbioflor 1
Signal transduction countsGenes 30 · HK 14 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key