Gene detail

HMPREF1354_RS02715

Histidine kinase, Classic

Enterococcus faecium 514 · GCF_000295615

ClassHKTypeClassicLength359 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295615#HMPREF1354_RS02715Stable P2CS identifier used across views.
GenomeGCF_000295615Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2691252Run 6 · 2956 sequences · id 100% · cov 80%
External referencesWP_002317394.1 · A0AAV3GYF7 · MIST4 HMPREF1354_RS02715RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length359 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage146 / 359 aa (40.7%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa359 aa
HisKA_3: 172-235 aa (64 aa)1HATPase_c: 275-356 aa (82 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
172-235 aa · 64 aa · 17.8% of protein
Raw tokenHisKA_3:172:5.94e-16:235:66:68
2 HATPase_c#2
275-356 aa · 82 aa · 22.8% of protein
Raw tokenHATPase_c:275:0.000000242:356:100:109
  • Raw architecture: HisKA_3:172:5.94e-16:235:66:68#HATPase_c:275:0.000000242:356:100:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000295615::NZ_JH812228.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15985-17720Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1354_00583RefSeq proteinWP_002317394.1
Context group IDGCF_000295615::NZ_JH812228.1::G00003
Context members
HMPREF1354_RS02715HMPREF1354_RS02720
Partner locus tags
HMPREF1354_RS02715HMPREF1354_RS02720
Partner old locus tags
HMPREF1354_00583HMPREF1354_00584
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002317394.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GYF7Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GYF7_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1354_RS02715Primary locus identifier stored in the genes table.
Old locus tagHMPREF1354_00583Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH812228.1Sequence record reported by the local genomic context database.
Genomic interval15 985-17 094 nt1 110 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 985-17 720 ntGCF_000295615::NZ_JH812228.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000295615::NZ_JH812228.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH812228.1All displayed genes belong to this local TCS context.
Neighborhood span15 985-17 720 nt1 736 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 985 nt17 720 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1354_RS02720GCF_000295615#HMPREF1354_RS02720
RRNarL

17 091-17 720 nt · Forward (+)

Old locus HMPREF1354_00584RefSeq WP_002289597.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2691252Run 6 · HK · 2956 sequences
Representative sequenceGCF_000172675#EFME1162_RS10350Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c_52 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2691252

Simplified PFAM architecture for HKOC_2691252

PFAM domain coverage: 150 / 369 aa (40.7%)

1 aa369 aa
HisKA_3: 182-245 aaHisKA_3HATPase_c_5: 279-364 aaHATPase_c_5
HisKA_3HATPase_c_5
  • Simplified architecture: HisKA_3 + HATPase_c_5
  • Raw architecture: HisKA_3[182-245] | HATPase_c_5[279-364]
  • Domain count: 2
  • Matched identifier: HKOC_2691252
  • Positioned domains: HisKA_3 182-245 ; HATPase_c_5 279-364
Cluster members and taxonomy
Visualization

Representative gene: GCF_000172675#EFME1162_RS10350

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 134 812 · GCF_000295615
AssemblyASM29561v2 · Scaffoldhaploid
Genome composition2 931 703 bp · 37,5% GCEnterococcus faecium 514
Signal transduction countsGenes 38 · HK 18 · RR 20CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key