1 His_kinase#1
315-393 aa · 79 aa · 15.1% of protein
Raw token
His_kinase:315:5.2e-20:393:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1354_RS03615
Histidine kinase, Classic
Enterococcus faecium 514 · GCF_000295615
ClassHKTypeClassicLength524 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295615#HMPREF1354_RS03615Stable P2CS identifier used across views.
GenomeGCF_000295615Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length524 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 524 aa (34.4%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa524 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
411-511 aa · 101 aa · 19.3% of protein
Raw token
HATPase_c:411:0.000000164:511:104:109- Raw architecture: His_kinase:315:5.2e-20:393:80:80#HATPase_c:411:0.000000164:511:104:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000295615::NZ_JH812243.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span331-2611Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1354_00784RefSeq proteinWP_002304873.1
Context group ID
GCF_000295615::NZ_JH812243.1::G00004Context members
HMPREF1354_RS03610HMPREF1354_RS03615
Partner locus tags
HMPREF1354_RS03610HMPREF1354_RS03615
Partner old locus tags
HMPREF1354_00783HMPREF1354_00784
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002304873.1Primary protein accession used for annex mappings.
UniProt accessionA0A132P204Primary UniProt accession resolved in the annex database.
UniProt IDA0A132P204_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1354_RS03615Primary locus identifier stored in the genes table.
Old locus tagHMPREF1354_00784Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH812243.1Sequence record reported by the local genomic context database.
Genomic interval1 037-2 611 nt1 575 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span331-2 611 ntGCF_000295615::NZ_JH812243.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295615::NZ_JH812243.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH812243.1All displayed genes belong to this local TCS context.
Neighborhood span331-2 611 nt2 281 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
331 nt2 611 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1354_RS03610GCF_000295615#HMPREF1354_RS03610
RRunclassified
331-1 059 nt · Reverse (-)
HMPREF1354_RS03615GCF_000295615#HMPREF1354_RS03615
HKClassicCurrent focus
1 037-2 611 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000148325#HMPREF9524_RS08285Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1377156
Simplified PFAM architecture for HKOC_1377156
PFAM domain coverage: 180 / 524 aa (34.4%)
1 aa524 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[315-392] | HATPase_c[411-512]
- Domain count: 2
- Matched identifier: HKOC_1377156
- Positioned domains: His_kinase 315-392 ; HATPase_c 411-512
Cluster members and taxonomy
Representative gene: GCF_000148325#HMPREF9524_RS08285
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 812 · GCF_000295615
AssemblyASM29561v2 · Scaffoldhaploid
Genome composition2 931 703 bp · 37,5% GCEnterococcus faecium 514
Signal transduction countsGenes 38 · HK 18 · RR 20CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key