1 HAMP#1
54-123 aa · 70 aa · 20.2% of protein
Raw token
HAMP:54:0.000000069:123:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1347_RS10865
Histidine kinase, Classic
Enterococcus faecium 504 · GCF_000295275
ClassHKTypeClassicLength347 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000295275#HMPREF1347_RS10865Stable P2CS identifier used across views.
GenomeGCF_000295275Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length347 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 347 aa (70.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa347 aa
Domain-by-domain annotation3 items
2 HisKA#2
129-194 aa · 66 aa · 19.0% of protein
Raw token
HisKA:129:0.0000000000000103:194:66:643 HATPase_c#3
238-344 aa · 107 aa · 30.8% of protein
Raw token
HATPase_c:238:2.43e-31:344:107:109- Raw architecture: HAMP:54:0.000000069:123:70:69#HisKA:129:0.0000000000000103:194:66:64#HATPase_c:238:2.43e-31:344:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000295275::NZ_JH811530.1::G00013
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span11318-12361Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1347_01619RefSeq proteinWP_002376765.1
Context group ID
GCF_000295275::NZ_JH811530.1::G00013Context members
HMPREF1347_RS10865
Partner locus tags
HMPREF1347_RS10865
Partner old locus tags
HMPREF1347_01619
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002376765.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1347_RS10865Primary locus identifier stored in the genes table.
Old locus tagHMPREF1347_01619Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH811530.1Sequence record reported by the local genomic context database.
Genomic interval11 318-12 361 nt1 044 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span11 318-12 361 ntGCF_000295275::NZ_JH811530.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295275::NZ_JH811530.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH811530.1All displayed genes belong to this local TCS context.
Neighborhood span11 318-12 361 nt1 044 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 318 nt12 361 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF1347_RS10865GCF_000295275#HMPREF1347_RS10865
HKClassicCurrent focus
11 318-12 361 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000295275#HMPREF1347_RS10865The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2810300
Simplified PFAM architecture for HKOC_2810300
PFAM domain coverage: 226 / 347 aa (65.1%)
1 aa347 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[71-123] | HisKA[129-193] | HATPase_c[238-345]
- Domain count: 3
- Matched identifier: HKOC_2810300
- Positioned domains: HAMP 71-123 ; HisKA 129-193 ; HATPase_c 238-345
Cluster members and taxonomy
Representative gene: GCF_000295275#HMPREF1347_RS10865
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 805 · GCF_000295275
AssemblyASM29527v2 · Scaffoldhaploid
Genome composition2 617 730 bp · 38,0% GCEnterococcus faecium 504
Signal transduction countsGenes 35 · HK 18 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key