1 His_kinase#1
375-454 aa · 80 aa · 13.9% of protein
Raw token
His_kinase:375:7.62e-27:454:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1347_RS09240
Histidine kinase, Classic
Enterococcus faecium 504 · GCF_000295275
ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000295275#HMPREF1347_RS09240Stable P2CS identifier used across views.
GenomeGCF_000295275Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 576 aa (30.6%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
473-568 aa · 96 aa · 16.7% of protein
Raw token
HATPase_c:473:0.00000000192:568:106:109- Raw architecture: His_kinase:375:7.62e-27:454:80:80#HATPase_c:473:0.00000000192:568:106:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000295275::NZ_JH811517.1::G00012
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span74745-76475Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1347_01254RefSeq proteinWP_002376475.1
Context group ID
GCF_000295275::NZ_JH811517.1::G00012Context members
HMPREF1347_RS09240
Partner locus tags
HMPREF1347_RS09240
Partner old locus tags
HMPREF1347_01254
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002376475.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1347_RS09240Primary locus identifier stored in the genes table.
Old locus tagHMPREF1347_01254Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH811517.1Sequence record reported by the local genomic context database.
Genomic interval74 745-76 475 nt1 731 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span74 745-76 475 ntGCF_000295275::NZ_JH811517.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295275::NZ_JH811517.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH811517.1All displayed genes belong to this local TCS context.
Neighborhood span74 745-76 475 nt1 731 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
74 745 nt76 475 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF1347_RS09240GCF_000295275#HMPREF1347_RS09240
HKClassicCurrent focus
74 745-76 475 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000295275#HMPREF1347_RS09240The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1183040
Simplified PFAM architecture for HKOC_1183040
PFAM domain coverage: 175 / 576 aa (30.4%)
1 aa576 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[376-454] | HATPase_c[473-568]
- Domain count: 2
- Matched identifier: HKOC_1183040
- Positioned domains: His_kinase 376-454 ; HATPase_c 473-568
Cluster members and taxonomy
Representative gene: GCF_000295275#HMPREF1347_RS09240
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 805 · GCF_000295275
AssemblyASM29527v2 · Scaffoldhaploid
Genome composition2 617 730 bp · 38,0% GCEnterococcus faecium 504
Signal transduction countsGenes 35 · HK 18 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key