1 HAMP#1
182-251 aa · 70 aa · 11.5% of protein
Raw token
HAMP:182:4.57e-18:251:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1347_RS06360
Histidine kinase, Classic
Enterococcus faecium 504 · GCF_000295275
ClassHKTypeClassicLength611 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295275#HMPREF1347_RS06360Stable P2CS identifier used across views.
GenomeGCF_000295275Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPPASHisKAHATPase_c
Protein length611 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage358 / 611 aa (58.6%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa611 aa
Domain-by-domain annotation4 items
2 PAS#2
261-368 aa · 108 aa · 17.7% of protein
Raw token
PAS:261:0.00000000226:368:113:1133 HisKA#3
377-444 aa · 68 aa · 11.1% of protein
Raw token
HisKA:377:1.03e-18:444:68:644 HATPase_c#4
493-604 aa · 112 aa · 18.3% of protein
Raw token
HATPase_c:493:1e-31:604:112:109- Raw architecture: HAMP:182:4.57e-18:251:70:69#PAS:261:0.00000000226:368:113:113#HisKA:377:1.03e-18:444:68:64#HATPase_c:493:1e-31:604:112:109
- Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000295275::NZ_JH811488.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span111068-113612Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1347_00614RefSeq proteinWP_002294131.1
Context group ID
GCF_000295275::NZ_JH811488.1::G00006Context members
HMPREF1347_RS06355HMPREF1347_RS06360
Partner locus tags
HMPREF1347_RS06355HMPREF1347_RS06360
Partner old locus tags
HMPREF1347_00613HMPREF1347_00614
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002294131.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GUQ9Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GUQ9_ENTFCDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1347_RS06360Primary locus identifier stored in the genes table.
Old locus tagHMPREF1347_00614Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH811488.1Sequence record reported by the local genomic context database.
Genomic interval111 777-113 612 nt1 836 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span111 068-113 612 ntGCF_000295275::NZ_JH811488.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295275::NZ_JH811488.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH811488.1All displayed genes belong to this local TCS context.
Neighborhood span111 068-113 612 nt2 545 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
111 068 nt113 612 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1347_RS06355GCF_000295275#HMPREF1347_RS06355
RROmpR
111 068-111 772 nt · Forward (+)
HMPREF1347_RS06360GCF_000295275#HMPREF1347_RS06360
HKClassicCurrent focus
111 777-113 612 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000157535#EFQG_RS13310Use this link to inspect the representative gene detail.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1000690
Simplified PFAM architecture for HKOC_1000690
PFAM domain coverage: 381 / 611 aa (62.4%)
1 aa611 aa
Cache_WalKHAMPPASHisKAHATPase_c
- Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
- Raw architecture: Cache_WalK[79-166] | HAMP[199-251] | PAS[262-323] | HisKA[378-444] | HATPase_c[493-603]
- Domain count: 5
- Matched identifier: HKOC_1000690
- Positioned domains: Cache_WalK 79-166 ; HAMP 199-251 ; PAS 262-323 ; HisKA 378-444 ; HATPase_c 493-603
Cluster members and taxonomy
Representative gene: GCF_000157535#EFQG_RS13310
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 805 · GCF_000295275
AssemblyASM29527v2 · Scaffoldhaploid
Genome composition2 617 730 bp · 38,0% GCEnterococcus faecium 504
Signal transduction countsGenes 35 · HK 18 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key