Gene detail

HMPREF1347_RS06135

Histidine kinase, Classic

Enterococcus faecium 504 · GCF_000295275

ClassHKTypeClassicLength359 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295275#HMPREF1347_RS06135Stable P2CS identifier used across views.
GenomeGCF_000295275Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2753128Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_002375879.1 · MIST4 HMPREF1347_RS06135RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length359 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage146 / 359 aa (40.7%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa359 aa
HisKA_3: 172-235 aa (64 aa)1HATPase_c: 275-356 aa (82 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
172-235 aa · 64 aa · 17.8% of protein
Raw tokenHisKA_3:172:7.88e-16:235:66:68
2 HATPase_c#2
275-356 aa · 82 aa · 22.8% of protein
Raw tokenHATPase_c:275:0.00000123:356:100:109
  • Raw architecture: HisKA_3:172:7.88e-16:235:66:68#HATPase_c:275:0.00000123:356:100:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000295275::NZ_JH811488.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span67784-69519Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1347_00565RefSeq proteinWP_002375879.1
Context group IDGCF_000295275::NZ_JH811488.1::G00004
Context members
HMPREF1347_RS06130HMPREF1347_RS06135
Partner locus tags
HMPREF1347_RS06130HMPREF1347_RS06135
Partner old locus tags
HMPREF1347_00564HMPREF1347_00565
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002375879.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1347_RS06135Primary locus identifier stored in the genes table.
Old locus tagHMPREF1347_00565Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH811488.1Sequence record reported by the local genomic context database.
Genomic interval68 410-69 519 nt1 110 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span67 784-69 519 ntGCF_000295275::NZ_JH811488.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000295275::NZ_JH811488.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH811488.1All displayed genes belong to this local TCS context.
Neighborhood span67 784-69 519 nt1 736 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
67 784 nt69 519 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1347_RS06130GCF_000295275#HMPREF1347_RS06130
RRNarL

67 784-68 413 nt · Reverse (-)

Old locus HMPREF1347_00564RefSeq WP_002289597.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2753128Run 6 · HK · 1 sequences
Representative sequenceGCF_000295275#HMPREF1347_RS06135The current gene is the representative for this cluster.
PFAM architectureHisKA_3 + HATPase_c_52 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2753128

Simplified PFAM architecture for HKOC_2753128

PFAM domain coverage: 113 / 359 aa (31.5%)

1 aa359 aa
HisKA_3: 172-235 aaHisKA_3HATPase_c_5: 306-354 aaHATPase_c_5
HisKA_3HATPase_c_5
  • Simplified architecture: HisKA_3 + HATPase_c_5
  • Raw architecture: HisKA_3[172-235] | HATPase_c_5[306-354]
  • Domain count: 2
  • Matched identifier: HKOC_2753128
  • Positioned domains: HisKA_3 172-235 ; HATPase_c_5 306-354
Cluster members and taxonomy
Visualization

Representative gene: GCF_000295275#HMPREF1347_RS06135

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 134 805 · GCF_000295275
AssemblyASM29527v2 · Scaffoldhaploid
Genome composition2 617 730 bp · 38,0% GCEnterococcus faecium 504
Signal transduction countsGenes 35 · HK 18 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key