1 HAMP#1
171-241 aa · 71 aa · 15.3% of protein
Raw token
HAMP:171:0.0000000129:241:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1347_RS05810
Histidine kinase, Classic
Enterococcus faecium 504 · GCF_000295275
ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295275#HMPREF1347_RS05810Stable P2CS identifier used across views.
GenomeGCF_000295275Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 464 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa464 aa
Domain-by-domain annotation3 items
2 HisKA#2
246-308 aa · 63 aa · 13.6% of protein
Raw token
HisKA:246:0.00000000000894:308:63:643 HATPase_c#3
353-464 aa · 112 aa · 24.1% of protein
Raw token
HATPase_c:353:4.46e-32:464:112:109- Raw architecture: HAMP:171:0.0000000129:241:71:69#HisKA:246:0.00000000000894:308:63:64#HATPase_c:353:4.46e-32:464:112:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000295275::NZ_JH811487.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span12681-14755Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1347_00493RefSeq proteinWP_002344913.1
Context group ID
GCF_000295275::NZ_JH811487.1::G00003Context members
HMPREF1347_RS05805HMPREF1347_RS05810
Partner locus tags
HMPREF1347_RS05805HMPREF1347_RS05810
Partner old locus tags
HMPREF1347_00492HMPREF1347_00493
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002344913.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1347_RS05810Primary locus identifier stored in the genes table.
Old locus tagHMPREF1347_00493Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH811487.1Sequence record reported by the local genomic context database.
Genomic interval13 361-14 755 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span12 681-14 755 ntGCF_000295275::NZ_JH811487.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295275::NZ_JH811487.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH811487.1All displayed genes belong to this local TCS context.
Neighborhood span12 681-14 755 nt2 075 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
12 681 nt14 755 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1347_RS05805GCF_000295275#HMPREF1347_RS05805
RROmpR
12 681-13 361 nt · Forward (+)
HMPREF1347_RS05810GCF_000295275#HMPREF1347_RS05810
HKClassicCurrent focus
13 361-14 755 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000295275#HMPREF1347_RS05810The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1783954
Simplified PFAM architecture for HKOC_1783954
PFAM domain coverage: 173 / 464 aa (37.3%)
1 aa464 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[246-308] | HATPase_c[354-463]
- Domain count: 2
- Matched identifier: HKOC_1783954
- Positioned domains: HisKA 246-308 ; HATPase_c 354-463
Cluster members and taxonomy
Representative gene: GCF_000295275#HMPREF1347_RS05810
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 805 · GCF_000295275
AssemblyASM29527v2 · Scaffoldhaploid
Genome composition2 617 730 bp · 38,0% GCEnterococcus faecium 504
Signal transduction countsGenes 35 · HK 18 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key