Gene detail

IEE_RS00445

Histidine kinase, Classic

Bacillus cereus BAG5X1-1 · GCF_000291295

ClassHKTypeClassicLength523 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000291295#IEE_RS00445Stable P2CS identifier used across views.
GenomeGCF_000291295Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1380054Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_002198721.1 · J8BQJ4 · MIST4 IEE_RS00445RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GAFGAF_3HisKA_3HATPase_c
Protein length523 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage413 / 523 aa (79.0%)Merged over positioned domains only.
Domain description1 GAF,1 GAF_3,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa523 aa
GAF: 29-166 aa (138 aa)1GAF_3: 203-318 aa (116 aa)2HisKA_3: 333-400 aa (68 aa)3HATPase_c: 433-523 aa (91 aa)4
Domain-by-domain annotation4 items
1 GAF#1
29-166 aa · 138 aa · 26.4% of protein
Raw tokenGAF:29:0.000000000000124:166:141:133
2 GAF_3#2
203-318 aa · 116 aa · 22.2% of protein
Raw tokenGAF_3:203:0.000000000375:318:124:129
3 HisKA_3#3
333-400 aa · 68 aa · 13.0% of protein
Raw tokenHisKA_3:333:6.04e-21:400:68:68
4 HATPase_c#4
433-523 aa · 91 aa · 17.4% of protein
Raw tokenHATPase_c:433:0.000000000901:523:106:109
  • Raw architecture: GAF:29:0.000000000000124:166:141:133#GAF_3:203:0.000000000375:318:124:129#HisKA_3:333:6.04e-21:400:68:68#HATPase_c:433:0.000000000901:523:106:109
  • Domain description: 1 GAF,1 GAF_3,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000291295::NZ_JH791996.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span97452-99691Genomic interval covered by the local TCS group.
Identifiers
Old locus tagIEE_00085RefSeq proteinWP_002198721.1
Context group IDGCF_000291295::NZ_JH791996.1::G00004
Context members
IEE_RS00445IEE_RS00450
Partner locus tags
IEE_RS00445IEE_RS00450
Partner old locus tags
IEE_00085IEE_00086
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002198721.1Primary protein accession used for annex mappings.
UniProt accessionJ8BQJ4Primary UniProt accession resolved in the annex database.
UniProt IDJ8BQJ4_BACCEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagIEE_RS00445Primary locus identifier stored in the genes table.
Old locus tagIEE_00085Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH791996.1Sequence record reported by the local genomic context database.
Genomic interval97 452-99 023 nt1 572 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span97 452-99 691 ntGCF_000291295::NZ_JH791996.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000291295::NZ_JH791996.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH791996.1All displayed genes belong to this local TCS context.
Neighborhood span97 452-99 691 nt2 240 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
97 452 nt99 691 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

IEE_RS00445GCF_000291295#IEE_RS00445
HKClassicCurrent focus

97 452-99 023 nt · Forward (+)

Old locus IEE_00085RefSeq WP_002198721.1
IEE_RS00450GCF_000291295#IEE_RS00450
RRNarL

99 044-99 691 nt · Forward (+)

Old locus IEE_00086RefSeq WP_002198722.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1380054Run 6 · HK · 5 sequences
Representative sequenceGCF_000291295#IEE_RS00445The current gene is the representative for this cluster.
PFAM architectureGAF_2 + GAF_3 + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1380054

Simplified PFAM architecture for HKOC_1380054

PFAM domain coverage: 413 / 523 aa (79.0%)

1 aa523 aa
GAF_2: 28-166 aaGAF_2GAF_3: 203-318 aaGAF_3HisKA_3: 333-400 aaHisKA_3HATPase_c: 434-523 aaHATPase_c
GAF_2GAF_3HisKA_3HATPase_c
  • Simplified architecture: GAF_2 + GAF_3 + HisKA_3 + HATPase_c
  • Raw architecture: GAF_2[28-166] | GAF_3[203-318] | HisKA_3[333-400] | HATPase_c[434-523]
  • Domain count: 4
  • Matched identifier: HKOC_1380054
  • Positioned domains: GAF_2 28-166 ; GAF_3 203-318 ; HisKA_3 333-400 ; HATPase_c 434-523
Cluster members and taxonomy
Visualization

Representative gene: GCF_000291295#IEE_RS00445

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 053 189 · GCF_000291295
AssemblyBaci_cere_BAG5X1-1_V1 · Scaffoldhaploid
Genome composition5 635 174 bp · 35,0% GCBacillus cereus BAG5X1-1
Signal transduction countsGenes 115 · HK 63 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key