1 Response_reg#1
5-107 aa · 103 aa · 20.5% of protein
Raw token
Response_reg:5:1.76e-25:107:103:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS15740
Response regulator, unclassified
Enterococcus faecium E4453 · GCF_000239095
ClassRRTypeunclassifiedLength502 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS15740Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regHTH_AraC
Protein length502 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage140 / 502 aa (27.9%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa502 aa
Domain-by-domain annotation2 items
2 HTH_AraC#2
461-497 aa · 37 aa · 7.4% of protein
Raw token
HTH_AraC:461:0.000000000273:497:37:42- Raw architecture: Response_reg:5:1.76e-25:107:103:111#HTH_AraC:461:0.000000000273:497:37:42
- Domain description: 1 Response_reg,1 HTH_AraC
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000328.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span31605-34845Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_1118RefSeq proteinWP_002323122.1
Context group ID
GCF_000239095::NZ_AEDZ01000328.1::G00001Context members
EFME4453_RS12140EFME4453_RS15740
Partner locus tags
EFME4453_RS12140EFME4453_RS15740
Partner old locus tags
EfmE4453_1117EfmE4453_1118
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002323122.1Primary protein accession used for annex mappings.
UniProt accessionA0AB73N3J0Primary UniProt accession resolved in the annex database.
UniProt IDA0AB73N3J0_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS15740Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_1118Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000328.1Sequence record reported by the local genomic context database.
Genomic interval33 337-34 845 nt1 509 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span31 605-34 845 ntGCF_000239095::NZ_AEDZ01000328.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000328.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000328.1All displayed genes belong to this local TCS context.
Neighborhood span31 605-34 845 nt3 241 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
31 605 nt34 845 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS12140GCF_000239095#EFME4453_RS12140
HKClassic
31 605-33 290 nt · Reverse (-)
EFME4453_RS15740GCF_000239095#EFME4453_RS15740
RRunclassifiedCurrent focus
33 337-34 845 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000239095#EFME4453_RS15740The current gene is the representative for this cluster.
PFAM architectureResponse_reg + HTH_182 domains in the representative PFAM annotation.
PFAM architecture for RROC_0155929
Simplified PFAM architecture for RROC_0155929
PFAM domain coverage: 182 / 502 aa (36.3%)
1 aa502 aa
Response_regHTH_18
- Simplified architecture: Response_reg + HTH_18
- Raw architecture: Response_reg[5-107] | HTH_18[419-497]
- Domain count: 2
- Matched identifier: RROC_0155929
- Positioned domains: Response_reg 5-107 ; Response_reg 5-107 ; HTH_18 419-497 ; HTH_18 419-497
Cluster members and taxonomy
Representative gene: GCF_000239095#EFME4453_RS15740
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key