1 Response_reg#1
5-89 aa · 85 aa · 34.6% of protein
Raw token
Response_reg:5:0.0000011:89:85:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS11655
Response regulator LytTR family
Enterococcus faecium E4453 · GCF_000239095
ClassRRTypeLytTRLength246 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000239095#EFME4453_RS11655Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regLytTR
Protein length246 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 246 aa (70.3%)Merged over positioned domains only.
Domain description1 Response_reg,1 LytTRSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa246 aa
Domain-by-domain annotation2 items
2 LytTR#2
141-228 aa · 88 aa · 35.8% of protein
Raw token
LytTR:141:0.00000000691:228:91:98- Raw architecture: Response_reg:5:0.0000011:89:85:111#LytTR:141:0.00000000691:228:91:98
- Domain description: 1 Response_reg,1 LytTR
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000239095::NZ_AEDZ01000323.1::G00002
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span1906-2646Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_1240RefSeq proteinWP_002291154.1
Context group ID
GCF_000239095::NZ_AEDZ01000323.1::G00002Context members
EFME4453_RS11655
Partner locus tags
EFME4453_RS11655
Partner old locus tags
EfmE4453_1240
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002291154.1Primary protein accession used for annex mappings.
UniProt accessionA0A242G058Primary UniProt accession resolved in the annex database.
UniProt IDA0A242G058_ENTFCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS11655Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_1240Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000323.1Sequence record reported by the local genomic context database.
Genomic interval1 906-2 646 nt741 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 906-2 646 ntGCF_000239095::NZ_AEDZ01000323.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000323.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000323.1All displayed genes belong to this local TCS context.
Neighborhood span1 906-2 646 nt741 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 906 nt2 646 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
EFME4453_RS11655GCF_000239095#EFME4453_RS11655
RRLytTRCurrent focus
1 906-2 646 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000172615#EFME980_RS08670Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + LytTR2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0769452
Simplified PFAM architecture for RROC_0769452
PFAM domain coverage: 198 / 246 aa (80.5%)
1 aa246 aa
Response_regLytTR
- Simplified architecture: Response_reg + LytTR
- Raw architecture: Response_reg[5-110] | LytTR[145-236]
- Domain count: 2
- Matched identifier: RROC_0769452
- Positioned domains: Response_reg 5-110 ; Response_reg 5-110 ; LytTR 145-236 ; LytTR 145-236
Cluster members and taxonomy
Representative gene: GCF_000172615#EFME980_RS08670
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key