1 HAMP#1
54-123 aa · 70 aa · 20.2% of protein
Raw token
HAMP:54:0.000000012:123:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS10945
Histidine kinase, Classic
Enterococcus faecium E4453 · GCF_000239095
ClassHKTypeClassicLength347 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS10945Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length347 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 347 aa (70.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa347 aa
Domain-by-domain annotation3 items
2 HisKA#2
129-194 aa · 66 aa · 19.0% of protein
Raw token
HisKA:129:0.00000000000000358:194:66:643 HATPase_c#3
238-344 aa · 107 aa · 30.8% of protein
Raw token
HATPase_c:238:1.58e-31:344:107:109- Raw architecture: HAMP:54:0.000000012:123:70:69#HisKA:129:0.00000000000000358:194:66:64#HATPase_c:238:1.58e-31:344:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000304.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6276-7990Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_2280RefSeq proteinWP_002296820.1
Context group ID
GCF_000239095::NZ_AEDZ01000304.1::G00003Context members
EFME4453_RS10940EFME4453_RS10945
Partner locus tags
EFME4453_RS10940EFME4453_RS10945
Partner old locus tags
EfmE4453_2279EfmE4453_2280
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002296820.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GSK5Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GSK5_ENTFCDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS10945Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_2280Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000304.1Sequence record reported by the local genomic context database.
Genomic interval6 947-7 990 nt1 044 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 276-7 990 ntGCF_000239095::NZ_AEDZ01000304.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000304.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000304.1All displayed genes belong to this local TCS context.
Neighborhood span6 276-7 990 nt1 715 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 276 nt7 990 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS10940GCF_000239095#EFME4453_RS10940
RROmpR
6 276-6 944 nt · Forward (+)
EFME4453_RS10945GCF_000239095#EFME4453_RS10945
HKClassicCurrent focus
6 947-7 990 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000148025#HMPREF9522_RS15750Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2810172
Simplified PFAM architecture for HKOC_2810172
PFAM domain coverage: 226 / 347 aa (65.1%)
1 aa347 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[71-123] | HisKA[129-193] | HATPase_c[238-345]
- Domain count: 3
- Matched identifier: HKOC_2810172
- Positioned domains: HAMP 71-123 ; HisKA 129-193 ; HATPase_c 238-345
Cluster members and taxonomy
Representative gene: GCF_000148025#HMPREF9522_RS15750
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key