1 Response_reg#1
6-119 aa · 114 aa · 23.6% of protein
Raw token
Response_reg:6:1.35e-24:119:114:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS09985
Response regulator, unclassified
Enterococcus faecium E4453 · GCF_000239095
ClassRRTypeunclassifiedLength483 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS09985Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regHTH_AraC
Protein length483 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage194 / 483 aa (40.2%)Merged over positioned domains only.
Domain description1 Response_reg,2 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa483 aa
Domain-by-domain annotation3 items
2 HTH_AraC#2
387-428 aa · 42 aa · 8.7% of protein
Raw token
HTH_AraC:387:0.0000000123:428:42:423 HTH_AraC#3
440-477 aa · 38 aa · 7.9% of protein
Raw token
HTH_AraC:440:0.00000000363:477:38:42- Raw architecture: Response_reg:6:1.35e-24:119:114:111#HTH_AraC:387:0.0000000123:428:42:42#HTH_AraC:440:0.00000000363:477:38:42
- Domain description: 1 Response_reg,2 HTH_AraC
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000274.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span135-3307Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_0042RefSeq proteinWP_002304851.1
Context group ID
GCF_000239095::NZ_AEDZ01000274.1::G00006Context members
EFME4453_RS09985EFME4453_RS09990
Partner locus tags
EFME4453_RS09985EFME4453_RS09990
Partner old locus tags
EfmE4453_0042EfmE4453_0043
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002304851.1Primary protein accession used for annex mappings.
UniProt accessionI3U538Primary UniProt accession resolved in the annex database.
UniProt IDI3U538_ENTFDDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS09985Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_0042Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000274.1Sequence record reported by the local genomic context database.
Genomic interval135-1 586 nt1 452 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span135-3 307 ntGCF_000239095::NZ_AEDZ01000274.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000274.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000274.1All displayed genes belong to this local TCS context.
Neighborhood span135-3 307 nt3 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
135 nt3 307 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS09985GCF_000239095#EFME4453_RS09985
RRunclassifiedCurrent focus
135-1 586 nt · Reverse (-)
EFME4453_RS09990GCF_000239095#EFME4453_RS09990
HKClassic
1 583-3 307 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS13165Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + HTH_182 domains in the representative PFAM annotation.
PFAM architecture for RROC_0177195
Simplified PFAM architecture for RROC_0177195
PFAM domain coverage: 190 / 483 aa (39.3%)
1 aa483 aa
Response_regHTH_18
- Simplified architecture: Response_reg + HTH_18
- Raw architecture: Response_reg[6-118] | HTH_18[402-478]
- Domain count: 2
- Matched identifier: RROC_0177195
- Positioned domains: Response_reg 6-118 ; Response_reg 6-118 ; HTH_18 402-478 ; HTH_18 402-478
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS13165
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key