1 HisKA#1
163-230 aa · 68 aa · 16.9% of protein
Raw token
HisKA:163:0.0000000000000439:230:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS09230
Histidine kinase, Classic
Enterococcus faecium E4453 · GCF_000239095
ClassHKTypeClassicLength402 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS09230Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length402 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 402 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa402 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
276-387 aa · 112 aa · 27.9% of protein
Raw token
HATPase_c:276:6.16e-27:387:113:109- Raw architecture: HisKA:163:0.0000000000000439:230:68:64#HATPase_c:276:6.16e-27:387:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000254.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1628-3512Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_0633RefSeq proteinWP_002295267.1
Context group ID
GCF_000239095::NZ_AEDZ01000254.1::G00007Context members
EFME4453_RS09230EFME4453_RS09235
Partner locus tags
EFME4453_RS09230EFME4453_RS09235
Partner old locus tags
EfmE4453_0633EfmE4453_0634
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002295267.1Primary protein accession used for annex mappings.
UniProt accessionQ3XYJ6Primary UniProt accession resolved in the annex database.
UniProt IDQ3XYJ6_ENTFDDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS09230Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_0633Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000254.1Sequence record reported by the local genomic context database.
Genomic interval1 628-2 836 nt1 209 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 628-3 512 ntGCF_000239095::NZ_AEDZ01000254.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000254.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000254.1All displayed genes belong to this local TCS context.
Neighborhood span1 628-3 512 nt1 885 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 628 nt3 512 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS09230GCF_000239095#EFME4453_RS09230
HKClassicCurrent focus
1 628-2 836 nt · Reverse (-)
EFME4453_RS09235GCF_000239095#EFME4453_RS09235
RROmpR
2 823-3 512 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS12560Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2422855
Simplified PFAM architecture for HKOC_2422855
PFAM domain coverage: 177 / 402 aa (44.0%)
1 aa402 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[164-229] | HATPase_c[276-386]
- Domain count: 2
- Matched identifier: HKOC_2422855
- Positioned domains: HisKA 164-229 ; HATPase_c 276-386
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS12560
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key