1 HAMP#1
201-253 aa · 53 aa · 11.0% of protein
Raw token
HAMP:201:0.0000119:253:53:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS07280
Histidine kinase, Classic
Enterococcus faecium E4453 · GCF_000239095
ClassHKTypeClassicLength483 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS07280Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length483 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 483 aa (50.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa483 aa
Domain-by-domain annotation3 items
2 His_kinase#2
268-347 aa · 80 aa · 16.6% of protein
Raw token
His_kinase:268:1.58e-27:347:80:803 HATPase_c#3
363-474 aa · 112 aa · 23.2% of protein
Raw token
HATPase_c:363:5.31e-16:474:113:109- Raw architecture: HAMP:201:0.0000119:253:53:69#His_kinase:268:1.58e-27:347:80:80#HATPase_c:363:5.31e-16:474:113:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000203.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5194-8203Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_0753RefSeq proteinWP_002288002.1
Context group ID
GCF_000239095::NZ_AEDZ01000203.1::G00011Context members
EFME4453_RS07280EFME4453_RS07285
Partner locus tags
EFME4453_RS07280EFME4453_RS07285
Partner old locus tags
EfmE4453_0753EfmE4453_0754
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002288002.1Primary protein accession used for annex mappings.
UniProt accessionQ3XZY5Primary UniProt accession resolved in the annex database.
UniProt IDQ3XZY5_ENTFDDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS07280Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_0753Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000203.1Sequence record reported by the local genomic context database.
Genomic interval5 194-6 645 nt1 452 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 194-8 203 ntGCF_000239095::NZ_AEDZ01000203.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000203.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000203.1All displayed genes belong to this local TCS context.
Neighborhood span5 194-8 203 nt3 010 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 194 nt8 203 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS07280GCF_000239095#EFME4453_RS07280
HKClassicCurrent focus
5 194-6 645 nt · Forward (+)
EFME4453_RS07285GCF_000239095#EFME4453_RS07285
RRunclassified
6 638-8 203 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS06445Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1594050
Simplified PFAM architecture for HKOC_1594050
PFAM domain coverage: 239 / 483 aa (49.5%)
1 aa483 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[204-253] | His_kinase[269-346] | HATPase_c[363-473]
- Domain count: 3
- Matched identifier: HKOC_1594050
- Positioned domains: HAMP 204-253 ; His_kinase 269-346 ; HATPase_c 363-473
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS06445
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key