1 Response_reg#1
4-104 aa · 101 aa · 48.3% of protein
Raw token
Response_reg:4:3.99e-20:104:101:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS05545
Response regulator NarL family
Enterococcus faecium E4453 · GCF_000239095
ClassRRTypeNarLLength209 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS05545Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regHTH_LUXR
Protein length209 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 209 aa (75.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_LUXRSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa209 aa
Domain-by-domain annotation2 items
2 HTH_LUXR#2
148-204 aa · 57 aa · 27.3% of protein
Raw token
HTH_LUXR:148:1.94e-19:204:57:58- Raw architecture: Response_reg:4:3.99e-20:104:101:111#HTH_LUXR:148:1.94e-19:204:57:58
- Domain description: 1 Response_reg,1 HTH_LUXR
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000158.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15975-17710Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_0492RefSeq proteinWP_002289597.1
Context group ID
GCF_000239095::NZ_AEDZ01000158.1::G00015Context members
EFME4453_RS05540EFME4453_RS05545
Partner locus tags
EFME4453_RS05540EFME4453_RS05545
Partner old locus tags
EfmE4453_0491EfmE4453_0492
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002289597.1Primary protein accession used for annex mappings.
UniProt accessionQ3XWT8Primary UniProt accession resolved in the annex database.
UniProt IDQ3XWT8_ENTFDDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS05545Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_0492Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000158.1Sequence record reported by the local genomic context database.
Genomic interval17 081-17 710 nt630 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 975-17 710 ntGCF_000239095::NZ_AEDZ01000158.1::G00015
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000158.1::G00015Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000158.1All displayed genes belong to this local TCS context.
Neighborhood span15 975-17 710 nt1 736 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 975 nt17 710 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS05540GCF_000239095#EFME4453_RS05540
HKClassic
15 975-17 084 nt · Forward (+)
EFME4453_RS05545GCF_000239095#EFME4453_RS05545
RRNarLCurrent focus
17 081-17 710 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS03055Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + GerE2 domains in the representative PFAM annotation.
PFAM architecture for RROC_2041258
Simplified PFAM architecture for RROC_2041258
PFAM domain coverage: 158 / 209 aa (75.6%)
1 aa209 aa
Response_regGerE
- Simplified architecture: Response_reg + GerE
- Raw architecture: Response_reg[4-106] | GerE[149-203]
- Domain count: 2
- Matched identifier: RROC_2041258
- Positioned domains: Response_reg 4-106 ; Response_reg 4-106 ; GerE 149-203 ; GerE 149-203
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS03055
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key