1 Response_reg#1
4-113 aa · 110 aa · 48.2% of protein
Raw token
Response_reg:4:8.52e-32:113:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS01820
Response regulator OmpR family
Enterococcus faecium E4453 · GCF_000239095
ClassRRTypeOmpRLength228 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS01820Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length228 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage186 / 228 aa (81.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa228 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
151-226 aa · 76 aa · 33.3% of protein
Raw token
Trans_reg_C:151:4.43e-29:226:77:77- Raw architecture: Response_reg:4:8.52e-32:113:111:111#Trans_reg_C:151:4.43e-29:226:77:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000048.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3722-5910Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_2741RefSeq proteinWP_002290973.1
Context group ID
GCF_000239095::NZ_AEDZ01000048.1::G00016Context members
EFME4453_RS01820EFME4453_RS01825
Partner locus tags
EFME4453_RS01820EFME4453_RS01825
Partner old locus tags
EfmE4453_2741EfmE4453_2742
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002290973.1Primary protein accession used for annex mappings.
UniProt accessionQ3XYQ6Primary UniProt accession resolved in the annex database.
UniProt IDQ3XYQ6_ENTFDDisplay identifier provided by UniProt.
GO / PubMed7 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS01820Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_2741Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000048.1Sequence record reported by the local genomic context database.
Genomic interval3 722-4 408 nt687 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 722-5 910 ntGCF_000239095::NZ_AEDZ01000048.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000048.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000048.1All displayed genes belong to this local TCS context.
Neighborhood span3 722-5 910 nt2 189 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 722 nt5 910 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS01820GCF_000239095#EFME4453_RS01820
RROmpRCurrent focus
3 722-4 408 nt · Forward (+)
EFME4453_RS01825GCF_000239095#EFME4453_RS01825
HKClassic
4 405-5 910 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS02900Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1302019
Simplified PFAM architecture for RROC_1302019
PFAM domain coverage: 184 / 228 aa (80.7%)
1 aa228 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[4-112] | Trans_reg_C[152-226]
- Domain count: 2
- Matched identifier: RROC_1302019
- Positioned domains: Response_reg 4-112 ; Response_reg 4-112 ; Trans_reg_C 152-226 ; Trans_reg_C 152-226
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS02900
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key