1 HAMP#1
182-251 aa · 70 aa · 11.5% of protein
Raw token
HAMP:182:4.32e-18:251:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS01715
Histidine kinase, Classic
Enterococcus faecium E4453 · GCF_000239095
ClassHKTypeClassicLength611 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS01715Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPPASHisKAHATPase_c
Protein length611 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage358 / 611 aa (58.6%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa611 aa
Domain-by-domain annotation4 items
2 PAS#2
261-368 aa · 108 aa · 17.7% of protein
Raw token
PAS:261:0.00000000218:368:113:1133 HisKA#3
377-444 aa · 68 aa · 11.1% of protein
Raw token
HisKA:377:9.4e-19:444:68:644 HATPase_c#4
493-604 aa · 112 aa · 18.3% of protein
Raw token
HATPase_c:493:7.06e-32:604:112:109- Raw architecture: HAMP:182:4.32e-18:251:70:69#PAS:261:0.00000000218:368:113:113#HisKA:377:9.4e-19:444:68:64#HATPase_c:493:7.06e-32:604:112:109
- Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000046.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2156-4700Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_2356RefSeq proteinWP_002288851.1
Context group ID
GCF_000239095::NZ_AEDZ01000046.1::G00017Context members
EFME4453_RS01710EFME4453_RS01715
Partner locus tags
EFME4453_RS01710EFME4453_RS01715
Partner old locus tags
EfmE4453_2355EfmE4453_2356
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002288851.1Primary protein accession used for annex mappings.
UniProt accessionQ3XYG9Primary UniProt accession resolved in the annex database.
UniProt IDQ3XYG9_ENTFDDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS01715Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_2356Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000046.1Sequence record reported by the local genomic context database.
Genomic interval2 865-4 700 nt1 836 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 156-4 700 ntGCF_000239095::NZ_AEDZ01000046.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000046.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000046.1All displayed genes belong to this local TCS context.
Neighborhood span2 156-4 700 nt2 545 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 156 nt4 700 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS01710GCF_000239095#EFME4453_RS01710
RROmpR
2 156-2 860 nt · Forward (+)
EFME4453_RS01715GCF_000239095#EFME4453_RS01715
HKClassicCurrent focus
2 865-4 700 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147315#HMPREF9527_RS11875Use this link to inspect the representative gene detail.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1000686
Simplified PFAM architecture for HKOC_1000686
PFAM domain coverage: 381 / 611 aa (62.4%)
1 aa611 aa
Cache_WalKHAMPPASHisKAHATPase_c
- Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
- Raw architecture: Cache_WalK[79-166] | HAMP[199-251] | PAS[262-323] | HisKA[378-444] | HATPase_c[493-603]
- Domain count: 5
- Matched identifier: HKOC_1000686
- Positioned domains: Cache_WalK 79-166 ; HAMP 199-251 ; PAS 262-323 ; HisKA 378-444 ; HATPase_c 493-603
Cluster members and taxonomy
Representative gene: GCF_000147315#HMPREF9527_RS11875
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key