1 Response_reg#1
4-116 aa · 113 aa · 53.8% of protein
Raw token
Response_reg:4:2.54e-27:116:113:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS00830
Response regulator NarL family
Enterococcus faecium E4453 · GCF_000239095
ClassRRTypeNarLLength210 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS00830Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regHTH_LUXR
Protein length210 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 210 aa (81.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_LUXRSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa210 aa
Domain-by-domain annotation2 items
2 HTH_LUXR#2
146-203 aa · 58 aa · 27.6% of protein
Raw token
HTH_LUXR:146:3.45e-24:203:58:58- Raw architecture: Response_reg:4:2.54e-27:116:113:111#HTH_LUXR:146:3.45e-24:203:58:58
- Domain description: 1 Response_reg,1 HTH_LUXR
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000025.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5768-7474Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_0270RefSeq proteinWP_002295404.1
Context group ID
GCF_000239095::NZ_AEDZ01000025.1::G00018Context members
EFME4453_RS00830EFME4453_RS00835
Partner locus tags
EFME4453_RS00830EFME4453_RS00835
Partner old locus tags
EfmE4453_0270EfmE4453_0271
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002295404.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3L646Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3L646_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS00830Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_0270Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000025.1Sequence record reported by the local genomic context database.
Genomic interval5 768-6 400 nt633 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 768-7 474 ntGCF_000239095::NZ_AEDZ01000025.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000025.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000025.1All displayed genes belong to this local TCS context.
Neighborhood span5 768-7 474 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 768 nt7 474 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS00830GCF_000239095#EFME4453_RS00830
RRNarLCurrent focus
5 768-6 400 nt · Reverse (-)
EFME4453_RS00835GCF_000239095#EFME4453_RS00835
HKClassic
6 407-7 474 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000415265#D357_RS11385Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + GerE2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1963564
Simplified PFAM architecture for RROC_1963564
PFAM domain coverage: 169 / 213 aa (79.3%)
1 aa213 aa
Response_regGerE
- Simplified architecture: Response_reg + GerE
- Raw architecture: Response_reg[4-116] | GerE[148-203]
- Domain count: 2
- Matched identifier: RROC_1963564
- Positioned domains: Response_reg 4-116 ; Response_reg 4-116 ; GerE 148-203 ; GerE 148-203
Cluster members and taxonomy
Representative gene: GCF_000415265#D357_RS11385
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key