Gene detail

CDM68_RS05025

Histidine kinase, Classic

Clostridioides difficile M68 · GCF_000210395

ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210395#CDM68_RS05025Stable P2CS identifier used across views.
GenomeGCF_000210395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2328157Run 6 · 256 sequences · id 100% · cov 80% · representative
External referencesWP_004453503.1 · A0A9P3YTN2 · MIST4 CDM68_RS05025RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 413 aa (42.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa413 aa
HisKA: 186-255 aa (70 aa)1HATPase_c: 302-407 aa (106 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
186-255 aa · 70 aa · 16.9% of protein
Raw tokenHisKA:186:0.000000000000825:255:70:64
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw tokenHATPase_c:302:1.36e-26:407:107:109
  • Raw architecture: HisKA:186:0.000000000000825:255:70:64#HATPase_c:302:1.36e-26:407:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210395::NC_017175.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1068210-1070145Genomic interval covered by the local TCS group.
Context group IDGCF_000210395::NC_017175.1::G00016
Context members
CDM68_RS05020CDM68_RS05025
Partner locus tags
CDM68_RS05020CDM68_RS05025
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004453503.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YTN2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YTN2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM68_RS05025Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017175.1Sequence record reported by the local genomic context database.
Genomic interval1 068 904-1 070 145 nt1 242 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 068 210-1 070 145 ntGCF_000210395::NC_017175.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210395::NC_017175.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017175.1All displayed genes belong to this local TCS context.
Neighborhood span1 068 210-1 070 145 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 068 210 nt1 070 145 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM68_RS05020GCF_000210395#CDM68_RS05020
RROmpR

1 068 210-1 068 893 nt · Forward (+)

RefSeq WP_004453504.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2328157Run 6 · HK · 256 sequences
Representative sequenceGCF_000210395#CDM68_RS05025The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2328157

Simplified PFAM architecture for HKOC_2328157

PFAM domain coverage: 172 / 413 aa (41.6%)

1 aa413 aa
HisKA: 193-255 aaHisKAHATPase_c: 302-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[193-255] | HATPase_c[302-410]
  • Domain count: 2
  • Matched identifier: HKOC_2328157
  • Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS05025

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 256 total members. Page 1 / 6.

GCF_000210395#CDM68_RS05025 (representative)
CDM68_RS05025 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000210415#CDCF5_RS05050
CDCF5_RS05050 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000235825#HMPREF1122_RS11155
HMPREF1122_RS11155 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000235925#HMPREF1123_RS13520
HMPREF1123_RS13520 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000449945#QIG_RS04700
QIG_RS04700 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000452125#QUY_RS04690
QUY_RS04690 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000452165#QW3_RS04610
QW3_RS04610 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000530915#BN167_RS05045
BN167_RS05045 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_000531625#BN168_RS04970
BN168_RS04970 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_001757585#BW25_RS11925
BW25_RS11925 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_001757625#BW27_RS08370
BW27_RS08370 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_001971875#BER36_RS05500
BER36_RS05500 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_001972195#BER37_RS05295
BER37_RS05295 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002301085#BGU06_RS06105
BGU06_RS06105 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002301435#BGU22_RS13950
BGU22_RS13950 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002301555#BGU29_RS02775
BGU29_RS02775 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002302945#BGV12_RS02880
BGV12_RS02880 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002303045#BGV18_RS01205
BGV18_RS01205 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002303155#BGV23_RS07835
BGV23_RS07835 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002303485#BGU64_RS15235
BGU64_RS15235 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002303545#BGU67_RS08635
BGU67_RS08635 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_002940825#AWN77_RS10830
AWN77_RS10830 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003095675#DDG63_RS05485
DDG63_RS05485 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003095695#DDG61_RS05755
DDG61_RS05755 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003324015#DVA89_RS13910
DVA89_RS13910 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003324025#DVA88_RS12225
DVA88_RS12225 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003324035#DVA87_RS15905
DVA87_RS15905 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326835#DVA92_RS14335
DVA92_RS14335 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326845#DVA91_RS00155
DVA91_RS00155 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326875#DVA94_RS07555
DVA94_RS07555 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326885#DVA93_RS15325
DVA93_RS15325 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326915#DVA96_RS14435
DVA96_RS14435 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326935#DVA97_RS07210
DVA97_RS07210 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326945#DVA98_RS04335
DVA98_RS04335 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326965#DVA99_RS05950
DVA99_RS05950 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003326985#DVB00_RS15730
DVB00_RS15730 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327015#DVB04_RS13755
DVB04_RS13755 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327025#DVB06_RS15795
DVB06_RS15795 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327055#DVB02_RS16035
DVB02_RS16035 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327065#DVB01_RS12990
DVB01_RS12990 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327105#DVB12_RS15155
DVB12_RS15155 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327115#DVB09_RS07555
DVB09_RS07555 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327145#DVB10_RS16700
DVB10_RS16700 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327165#DVB07_RS16660
DVB07_RS16660 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327185#DVB14_RS12490
DVB14_RS12490 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327205#DVB16_RS08095
DVB16_RS08095 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327215#DVB15_RS13725
DVB15_RS13725 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327265#DVB18_RS12225
DVB18_RS12225 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327325#DVB05_RS14575
DVB05_RS14575 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2
GCF_003327345#DVB13_RS12615
DVB13_RS12615 · HK · Classic
RefSeq: WP_004453503.1
UniProt: A0A9P3YTN2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 037 · GCF_000210395
AssemblyASM21039v1 · Chromosomehaploid
Genome composition4 308 325 bp · 29,0% GCClostridioides difficile M68
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key