1 HisKA#1
186-255 aa · 70 aa · 16.9% of protein
Raw token
HisKA:186:0.000000000000825:255:70:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DVB05_RS14575
Histidine kinase, Classic
Clostridioides difficile · GCF_003327325
ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003327325#DVB05_RS14575Stable P2CS identifier used across views.
GenomeGCF_003327325Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 413 aa (42.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa413 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw token
HATPase_c:302:1.36e-26:407:107:109- Raw architecture: HisKA:186:0.000000000000825:255:70:64#HATPase_c:302:1.36e-26:407:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003327325::NZ_QNWB01000013.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span65436-67371Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_003327325::NZ_QNWB01000013.1::G00004Context members
DVB05_RS14570DVB05_RS14575
Partner locus tags
DVB05_RS14570DVB05_RS14575
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004453503.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YTN2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YTN2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDVB05_RS14575Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_QNWB01000013.1Sequence record reported by the local genomic context database.
Genomic interval66 130-67 371 nt1 242 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span65 436-67 371 ntGCF_003327325::NZ_QNWB01000013.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003327325::NZ_QNWB01000013.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QNWB01000013.1All displayed genes belong to this local TCS context.
Neighborhood span65 436-67 371 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
65 436 nt67 371 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DVB05_RS14570GCF_003327325#DVB05_RS14570
RROmpR
65 436-66 119 nt · Forward (+)
DVB05_RS14575GCF_003327325#DVB05_RS14575
HKClassicCurrent focus
66 130-67 371 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS05025Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2328157
Simplified PFAM architecture for HKOC_2328157
PFAM domain coverage: 172 / 413 aa (41.6%)
1 aa413 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[193-255] | HATPase_c[302-410]
- Domain count: 2
- Matched identifier: HKOC_2328157
- Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS05025
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003327325
AssemblyASM332732v1 · Contighaploid
Genome composition4 266 507 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 50 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key