1 HisKA#1
186-255 aa · 70 aa · 16.9% of protein
Raw token
HisKA:186:0.000000000000825:255:70:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BER37_RS05295
Histidine kinase, Classic
Clostridioides difficile · GCF_001972195
ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001972195#BER37_RS05295Stable P2CS identifier used across views.
GenomeGCF_001972195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 413 aa (42.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa413 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw token
HATPase_c:302:1.36e-26:407:107:109- Raw architecture: HisKA:186:0.000000000000825:255:70:64#HATPase_c:302:1.36e-26:407:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001972195::NZ_MTWI01000001.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1103071-1105006Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBER37_001038RefSeq proteinWP_004453503.1
Context group ID
GCF_001972195::NZ_MTWI01000001.1::G00016Context members
BER37_RS05290BER37_RS05295
Partner locus tags
BER37_RS05290BER37_RS05295
Partner old locus tags
BER37_001037BER37_001038
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004453503.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YTN2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YTN2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBER37_RS05295Primary locus identifier stored in the genes table.
Old locus tagBER37_001038Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MTWI01000001.1Sequence record reported by the local genomic context database.
Genomic interval1 103 765-1 105 006 nt1 242 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 103 071-1 105 006 ntGCF_001972195::NZ_MTWI01000001.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001972195::NZ_MTWI01000001.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MTWI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 103 071-1 105 006 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 103 071 nt1 105 006 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BER37_RS05290GCF_001972195#BER37_RS05290
RROmpR
1 103 071-1 103 754 nt · Forward (+)
BER37_RS05295GCF_001972195#BER37_RS05295
HKClassicCurrent focus
1 103 765-1 105 006 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS05025Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2328157
Simplified PFAM architecture for HKOC_2328157
PFAM domain coverage: 172 / 413 aa (41.6%)
1 aa413 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[193-255] | HATPase_c[302-410]
- Domain count: 2
- Matched identifier: HKOC_2328157
- Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS05025
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_001972195
AssemblyASM197219v1 · Contighaploid
Genome composition4 278 990 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key