1 HisKA#1
345-411 aa · 67 aa · 9.2% of protein
Raw token
HisKA:345:0.0000000000000266:411:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
RTO_RS01245
Histidine kinase, Hybrid
[Ruminococcus] torques L2-14 · GCF_000210035
ClassHKTypeHybridLength730 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210035#RTO_RS01245Stable P2CS identifier used across views.
GenomeGCF_000210035Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length730 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 730 aa (41.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa730 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
458-576 aa · 119 aa · 16.3% of protein
Raw token
HATPase_c:458:3.07e-27:576:119:1093 Response_reg#3
599-716 aa · 118 aa · 16.2% of protein
Raw token
Response_reg:599:2.01e-29:716:118:111- Raw architecture: HisKA:345:0.0000000000000266:411:67:64#HATPase_c:458:3.07e-27:576:119:109#Response_reg:599:2.01e-29:716:118:111
- Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000210035::NC_021015.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span254098-257782Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000210035::NC_021015.1::G00003Context members
RTO_RS01245RTO_RS01250
Partner locus tags
RTO_RS01245RTO_RS01250
Partner old locus tags
RTO_02680
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_243441180.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagRTO_RS01245Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_021015.1Sequence record reported by the local genomic context database.
Genomic interval254 098-256 290 nt2 193 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span254 098-257 782 ntGCF_000210035::NC_021015.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000210035::NC_021015.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_021015.1All displayed genes belong to this local TCS context.
Neighborhood span254 098-257 782 nt3 685 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
254 098 nt257 782 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
RTO_RS01245GCF_000210035#RTO_RS01245
HKHybridCurrent focus
254 098-256 290 nt · Forward (+)
RTO_RS01250GCF_000210035#RTO_RS01250
RRRpfG
256 283-257 782 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210035#RTO_RS01245The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0712153
Simplified PFAM architecture for HKOC_0712153
PFAM domain coverage: 301 / 730 aa (41.2%)
1 aa730 aa
HisKAHATPase_cResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg
- Raw architecture: HisKA[345-411] | HATPase_c[459-575] | Response_reg[599-715]
- Domain count: 3
- Matched identifier: HKOC_0712153
- Positioned domains: HisKA 345-411 ; HATPase_c 459-575 ; Response_reg 599-715
Cluster members and taxonomy
Representative gene: GCF_000210035#RTO_RS01245
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 657 313 · GCF_000210035
AssemblyASM21003v1 · Chromosomehaploid
Genome composition3 341 681 bp · 41,0% GC[Ruminococcus] torques L2-14
Signal transduction countsGenes 63 · HK 30 · RR 32CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key