1 HisKA#1
206-271 aa · 66 aa · 7.4% of protein
Raw token
HisKA:206:8.98e-19:271:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROI_RS01065
Histidine kinase, Hybrid
Roseburia intestinalis M50/1 · GCF_000209995
ClassHKTypeHybridLength891 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000209995#ROI_RS01065Stable P2CS identifier used across views.
GenomeGCF_000209995Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length891 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage289 / 891 aa (32.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa891 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
318-434 aa · 117 aa · 13.1% of protein
Raw token
HATPase_c:318:2.7e-29:434:117:1093 Response_reg#3
467-572 aa · 106 aa · 11.9% of protein
Raw token
Response_reg:467:8.17e-21:572:106:111- Raw architecture: HisKA:206:8.98e-19:271:66:64#HATPase_c:318:2.7e-29:434:117:109#Response_reg:467:8.17e-21:572:106:111
- Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_000209995::NC_021040.1::G00005
Group size33 locus tags listed below.
HK / RR2 / 1Counts resolved for the local TCS neighborhood.
Context span216169-222597Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROI_02340RefSeq proteinWP_015559429.1
Context group ID
GCF_000209995::NC_021040.1::G00005Context members
ROI_RS01055ROI_RS01060ROI_RS01065
Partner locus tags
ROI_RS01055ROI_RS01060ROI_RS01065
Partner old locus tags
ROI_02320ROI_02330ROI_02340
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_015559429.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROI_RS01065Primary locus identifier stored in the genes table.
Old locus tagROI_02340Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_021040.1Sequence record reported by the local genomic context database.
Genomic interval219 922-222 597 nt2 676 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span216 169-222 597 ntGCF_000209995::NC_021040.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000209995::NC_021040.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_021040.1All displayed genes belong to this local TCS context.
Neighborhood span216 169-222 597 nt6 429 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
216 169 nt222 597 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
ROI_RS01055GCF_000209995#ROI_RS01055
RRRpfG
216 169-217 221 nt · Forward (+)
ROI_RS01060GCF_000209995#ROI_RS01060
HKUnorthodox
217 233-219 929 nt · Forward (+)
ROI_RS01065GCF_000209995#ROI_RS01065
HKHybridCurrent focus
219 922-222 597 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000209995#ROI_RS01065The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + DegV4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0426828
Simplified PFAM architecture for HKOC_0426828
PFAM domain coverage: 561 / 891 aa (63.0%)
1 aa891 aa
HisKAHATPase_cResponse_regDegV
- Simplified architecture: HisKA + HATPase_c + Response_reg + DegV
- Raw architecture: HisKA[206-271] | HATPase_c[318-433] | Response_reg[467-572] | DegV[617-889]
- Domain count: 4
- Matched identifier: HKOC_0426828
- Positioned domains: HisKA 206-271 ; HATPase_c 318-433 ; Response_reg 467-572 ; DegV 617-889
Cluster members and taxonomy
Representative gene: GCF_000209995#ROI_RS01065
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 657 315 · GCF_000209995
AssemblyASM20999v1 · Chromosomehaploid
Genome composition4 143 550 bp · 42,5% GCRoseburia intestinalis M50/1
Signal transduction countsGenes 106 · HK 45 · RR 57CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key