Gene detail

HMPREF9475_RS17595

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength801 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS17595Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0554218Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_003510221.1 · MIST4 HMPREF9475_RS17595RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length801 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage382 / 801 aa (47.7%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa801 aa
PAS_3: 172-235 aa (64 aa)1HisKA: 404-486 aa (83 aa)2HATPase_c: 534-650 aa (117 aa)3Response_reg: 679-796 aa (118 aa)4
Domain-by-domain annotation4 items
1 PAS_3#1
172-235 aa · 64 aa · 8.0% of protein
Raw tokenPAS_3:172:0.000000747:235:64:89
2 HisKA#2
404-486 aa · 83 aa · 10.4% of protein
Raw tokenHisKA:404:0.0000000000184:486:83:64
3 HATPase_c#3
534-650 aa · 117 aa · 14.6% of protein
Raw tokenHATPase_c:534:1.65e-32:650:117:109
4 Response_reg#4
679-796 aa · 118 aa · 14.7% of protein
Raw tokenResponse_reg:679:4.06e-30:796:118:111
  • Raw architecture: PAS_3:172:0.000000747:235:64:89#HisKA:404:0.0000000000184:486:83:64#HATPase_c:534:1.65e-32:650:117:109#Response_reg:679:4.06e-30:796:118:111
  • Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834364.1::G00061
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1317-3722Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_03445RefSeq proteinWP_003510221.1
Context group IDGCF_000189615::NZ_GL834364.1::G00061
Context members
HMPREF9475_RS17595
Partner locus tags
HMPREF9475_RS17595
Partner old locus tags
HMPREF9475_03445
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003510221.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS17595Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_03445Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834364.1Sequence record reported by the local genomic context database.
Genomic interval1 317-3 722 nt2 406 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 317-3 722 ntGCF_000189615::NZ_GL834364.1::G00061

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834364.1::G00061

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834364.1All displayed genes belong to this local TCS context.
Neighborhood span1 317-3 722 nt2 406 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 317 nt3 722 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0554218Run 6 · HK · 2 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS17595The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0554218

Simplified PFAM architecture for HKOC_0554218

PFAM domain coverage: 314 / 801 aa (39.2%)

1 aa801 aa
HisKA: 404-486 aaHisKAHATPase_c: 534-649 aaHATPase_cResponse_reg: 679-793 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[404-486] | HATPase_c[534-649] | Response_reg[679-793]
  • Domain count: 3
  • Matched identifier: HKOC_0554218
  • Positioned domains: HisKA 404-486 ; HATPase_c 534-649 ; Response_reg 679-793
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS17595

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key