1 HisKA#1
146-214 aa · 69 aa · 18.4% of protein
Raw token
HisKA:146:0.00000000000152:214:69:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9475_RS00645
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14673 · GCF_000189615
ClassHKTypeClassicLength374 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189615#HMPREF9475_RS00645Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length374 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 374 aa (48.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa374 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
258-368 aa · 111 aa · 29.7% of protein
Raw token
HATPase_c:258:1.73e-25:368:112:109- Raw architecture: HisKA:146:0.00000000000152:214:69:64#HATPase_c:258:1.73e-25:368:112:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189615::NZ_GL834357.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span158088-159915Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_00125RefSeq proteinWP_003498252.1
Context group ID
GCF_000189615::NZ_GL834357.1::G00004Context members
HMPREF9475_RS00640HMPREF9475_RS00645
Partner locus tags
HMPREF9475_RS00640HMPREF9475_RS00645
Partner old locus tags
HMPREF9475_00124HMPREF9475_00125
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003498252.1Primary protein accession used for annex mappings.
UniProt accessionE7GIA9Primary UniProt accession resolved in the annex database.
UniProt IDE7GIA9_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9475_RS00645Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_00125Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834357.1Sequence record reported by the local genomic context database.
Genomic interval158 791-159 915 nt1 125 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span158 088-159 915 ntGCF_000189615::NZ_GL834357.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189615::NZ_GL834357.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834357.1All displayed genes belong to this local TCS context.
Neighborhood span158 088-159 915 nt1 828 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
158 088 nt159 915 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9475_RS00640GCF_000189615#HMPREF9475_RS00640
RROmpR
158 088-158 801 nt · Reverse (-)
HMPREF9475_RS00645GCF_000189615#HMPREF9475_RS00645
HKClassicCurrent focus
158 791-159 915 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS03380Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2657528
Simplified PFAM architecture for HKOC_2657528
PFAM domain coverage: 287 / 374 aa (76.7%)
1 aa374 aa
DUF4118HisKAHATPase_c
- Simplified architecture: DUF4118 + HisKA + HATPase_c
- Raw architecture: DUF4118[25-134] | HisKA[147-213] | HATPase_c[259-368]
- Domain count: 3
- Matched identifier: HKOC_2657528
- Positioned domains: DUF4118 25-134 ; HisKA 147-213 ; HATPase_c 259-368
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS03380
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key