Gene detail

HMPREF9475_RS00615

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeClassicLength563 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189615#HMPREF9475_RS00615Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_1244698Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_003505807.1 · MIST4 HMPREF9475_RS00615RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length563 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 563 aa (45.8%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa563 aa
HAMP: 269-345 aa (77 aa)1His_kinase: 361-438 aa (78 aa)2HATPase_c: 455-557 aa (103 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
269-345 aa · 77 aa · 13.7% of protein
Raw tokenHAMP:269:0.0000000206:345:77:69
2 His_kinase#2
361-438 aa · 78 aa · 13.9% of protein
Raw tokenHis_kinase:361:5.48e-28:438:79:80
3 HATPase_c#3
455-557 aa · 103 aa · 18.3% of protein
Raw tokenHATPase_c:455:0.0000000347:557:106:109
  • Raw architecture: HAMP:269:0.0000000206:345:77:69#His_kinase:361:5.48e-28:438:79:80#HATPase_c:455:0.0000000347:557:106:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189615::NZ_GL834357.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span148460-150943Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_00119RefSeq proteinWP_003505807.1
Context group IDGCF_000189615::NZ_GL834357.1::G00003
Context members
HMPREF9475_RS00615HMPREF9475_RS00620
Partner locus tags
HMPREF9475_RS00615HMPREF9475_RS00620
Partner old locus tags
HMPREF9475_00119HMPREF9475_00120
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003505807.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS00615Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_00119Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834357.1Sequence record reported by the local genomic context database.
Genomic interval148 460-150 151 nt1 692 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span148 460-150 943 ntGCF_000189615::NZ_GL834357.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834357.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834357.1All displayed genes belong to this local TCS context.
Neighborhood span148 460-150 943 nt2 484 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
148 460 nt150 943 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9475_RS00620GCF_000189615#HMPREF9475_RS00620
RRunclassified

150 155-150 943 nt · Forward (+)

Old locus HMPREF9475_00120RefSeq WP_003505809.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1244698Run 6 · HK · 2 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS00615The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1244698

Simplified PFAM architecture for HKOC_1244698

PFAM domain coverage: 124 / 563 aa (22.0%)

1 aa563 aa
HAMP: 300-345 aaHAMPHis_kinase: 361-438 aaHis_kinase
HAMPHis_kinase
  • Simplified architecture: HAMP + His_kinase
  • Raw architecture: HAMP[300-345] | His_kinase[361-438]
  • Domain count: 2
  • Matched identifier: HKOC_1244698
  • Positioned domains: HAMP 300-345 ; His_kinase 361-438
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS00615

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key