Gene detail

HMPREF9475_RS14535

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeClassicLength466 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189615#HMPREF9475_RS14535Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_1761823Run 6 · 13 sequences · id 100% · cov 80% · representative
External referencesWP_003509464.1 · MIST4 HMPREF9475_RS14535RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length466 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 466 aa (52.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa466 aa
HAMP: 170-240 aa (71 aa)1HisKA: 244-307 aa (64 aa)2HATPase_c: 353-462 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
170-240 aa · 71 aa · 15.2% of protein
Raw tokenHAMP:170:0.00000000000725:240:71:69
2 HisKA#2
244-307 aa · 64 aa · 13.7% of protein
Raw tokenHisKA:244:0.000000000526:307:64:64
3 HATPase_c#3
353-462 aa · 110 aa · 23.6% of protein
Raw tokenHATPase_c:353:3.12e-33:462:110:109
  • Raw architecture: HAMP:170:0.00000000000725:240:71:69#HisKA:244:0.000000000526:307:64:64#HATPase_c:353:3.12e-33:462:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189615::NZ_GL834361.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span327241-329339Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_02855RefSeq proteinWP_003509464.1
Context group IDGCF_000189615::NZ_GL834361.1::G00052
Context members
HMPREF9475_RS14535HMPREF9475_RS14540
Partner locus tags
HMPREF9475_RS14535HMPREF9475_RS14540
Partner old locus tags
HMPREF9475_02855HMPREF9475_02856
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003509464.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS14535Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_02855Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834361.1Sequence record reported by the local genomic context database.
Genomic interval327 241-328 641 nt1 401 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span327 241-329 339 ntGCF_000189615::NZ_GL834361.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834361.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834361.1All displayed genes belong to this local TCS context.
Neighborhood span327 241-329 339 nt2 099 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
327 241 nt329 339 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9475_RS14540GCF_000189615#HMPREF9475_RS14540
RROmpR

328 638-329 339 nt · Reverse (-)

Old locus HMPREF9475_02856RefSeq WP_003499900.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1761823Run 6 · HK · 13 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS14535The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1761823

Simplified PFAM architecture for HKOC_1761823

PFAM domain coverage: 227 / 466 aa (48.7%)

1 aa466 aa
HAMP: 187-240 aaHAMPHisKA: 244-305 aaHisKAHATPase_c: 354-464 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[187-240] | HisKA[244-305] | HATPase_c[354-464]
  • Domain count: 3
  • Matched identifier: HKOC_1761823
  • Positioned domains: HAMP 187-240 ; HisKA 244-305 ; HATPase_c 354-464
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS14535

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key