Gene detail

HMPREF9475_RS13225

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength714 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS13225Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0716858Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_003509111.1 · MIST4 HMPREF9475_RS13225RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_2HisKAHATPase_cResponse_reg
Protein length714 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage410 / 714 aa (57.4%)Merged over positioned domains only.
Domain description1 sCache_2,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa714 aa
sCache_2: 162-274 aa (113 aa)1HisKA: 342-403 aa (62 aa)2HATPase_c: 449-573 aa (125 aa)3Response_reg: 599-708 aa (110 aa)4
Domain-by-domain annotation4 items
1 sCache_2#1
162-274 aa · 113 aa · 15.8% of protein
Raw tokensCache_2:162:0.000000000157:274:115:152
2 HisKA#2
342-403 aa · 62 aa · 8.7% of protein
Raw tokenHisKA:342:0.000000112:403:62:64
3 HATPase_c#3
449-573 aa · 125 aa · 17.5% of protein
Raw tokenHATPase_c:449:4.62e-26:573:126:109
4 Response_reg#4
599-708 aa · 110 aa · 15.4% of protein
Raw tokenResponse_reg:599:0.0000000000000324:708:114:111
  • Raw architecture: sCache_2:162:0.000000000157:274:115:152#HisKA:342:0.000000112:403:62:64#HATPase_c:449:4.62e-26:573:126:109#Response_reg:599:0.0000000000000324:708:114:111
  • Domain description: 1 sCache_2,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834361.1::G00046
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span27445-29589Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_02597RefSeq proteinWP_003509111.1
Context group IDGCF_000189615::NZ_GL834361.1::G00046
Context members
HMPREF9475_RS13225
Partner locus tags
HMPREF9475_RS13225
Partner old locus tags
HMPREF9475_02597
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003509111.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS13225Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_02597Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834361.1Sequence record reported by the local genomic context database.
Genomic interval27 445-29 589 nt2 145 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span27 445-29 589 ntGCF_000189615::NZ_GL834361.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834361.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834361.1All displayed genes belong to this local TCS context.
Neighborhood span27 445-29 589 nt2 145 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 445 nt29 589 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0716858Run 6 · HK · 10 sequences
Representative sequenceGCF_001406475#ARA57_RS14335Use this link to inspect the representative gene detail.
PFAM architecturesCache_2 + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0716858

Simplified PFAM architecture for HKOC_0716858

PFAM domain coverage: 416 / 728 aa (57.1%)

1 aa728 aa
sCache_2: 169-285 aasCache_2HisKA: 357-419 aaHisKAHATPase_c: 463-588 aaHATPase_cResponse_reg: 613-722 aaResponse_reg
sCache_2HisKAHATPase_cResponse_reg
  • Simplified architecture: sCache_2 + HisKA + HATPase_c + Response_reg
  • Raw architecture: sCache_2[169-285] | HisKA[357-419] | HATPase_c[463-588] | Response_reg[613-722]
  • Domain count: 4
  • Matched identifier: HKOC_0716858
  • Positioned domains: sCache_2 169-285 ; HisKA 357-419 ; HATPase_c 463-588 ; Response_reg 613-722
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406475#ARA57_RS14335

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key