Gene detail

HMPREF9475_RS09840

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength939 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189615#HMPREF9475_RS09840Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0341182Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_003508295.1 · MIST4 HMPREF9475_RS09840RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length939 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage431 / 939 aa (45.9%)Merged over positioned domains only.
Domain description2 PAS_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa939 aa
PAS_3: 313-379 aa (67 aa)1PAS_3: 458-520 aa (63 aa)2HisKA: 553-619 aa (67 aa)3HATPase_c: 666-783 aa (118 aa)4Response_reg: 822-937 aa (116 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
313-379 aa · 67 aa · 7.1% of protein
Raw tokenPAS_3:313:0.000021:379:68:89
2 PAS_3#2
458-520 aa · 63 aa · 6.7% of protein
Raw tokenPAS_3:458:0.000031:520:64:89
3 HisKA#3
553-619 aa · 67 aa · 7.1% of protein
Raw tokenHisKA:553:2.56e-17:619:67:64
4 HATPase_c#4
666-783 aa · 118 aa · 12.6% of protein
Raw tokenHATPase_c:666:1.64e-30:783:118:109
5 Response_reg#5
822-937 aa · 116 aa · 12.4% of protein
Raw tokenResponse_reg:822:1.55e-25:937:116:111
  • Raw architecture: PAS_3:313:0.000021:379:68:89#PAS_3:458:0.000031:520:64:89#HisKA:553:2.56e-17:619:67:64#HATPase_c:666:1.64e-30:783:118:109#Response_reg:822:1.55e-25:937:116:111
  • Domain description: 2 PAS_3,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189615::NZ_GL834359.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span565405-569100Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_01947RefSeq proteinWP_003508295.1
Context group IDGCF_000189615::NZ_GL834359.1::G00039
Context members
HMPREF9475_RS09835HMPREF9475_RS09840
Partner locus tags
HMPREF9475_RS09835HMPREF9475_RS09840
Partner old locus tags
HMPREF9475_01946HMPREF9475_01947
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003508295.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS09840Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_01947Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834359.1Sequence record reported by the local genomic context database.
Genomic interval566 281-569 100 nt2 820 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span565 405-569 100 ntGCF_000189615::NZ_GL834359.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834359.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834359.1All displayed genes belong to this local TCS context.
Neighborhood span565 405-569 100 nt3 696 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
565 405 nt569 100 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9475_RS09835GCF_000189615#HMPREF9475_RS09835
RROmpR

565 405-566 100 nt · Forward (+)

Old locus HMPREF9475_01946RefSeq WP_003508294.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0341182Run 6 · HK · 5 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS09840The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0341182

Simplified PFAM architecture for HKOC_0341182

PFAM domain coverage: 300 / 939 aa (31.9%)

1 aa939 aa
HisKA: 553-619 aaHisKAHATPase_c: 666-783 aaHATPase_cResponse_reg: 822-936 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[553-619] | HATPase_c[666-783] | Response_reg[822-936]
  • Domain count: 3
  • Matched identifier: HKOC_0341182
  • Positioned domains: HisKA 553-619 ; HATPase_c 666-783 ; Response_reg 822-936
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS09840

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key