Gene detail

HMPREF9475_RS08840

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeClassicLength459 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS08840Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_1845579Run 6 · 47 sequences · id 100% · cov 80%
External referencesWP_003498628.1 · E7GIS1 · MIST4 HMPREF9475_RS08840RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length459 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage244 / 459 aa (53.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa459 aa
HAMP: 158-227 aa (70 aa)1HisKA: 232-291 aa (60 aa)2HATPase_c: 340-453 aa (114 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
158-227 aa · 70 aa · 15.3% of protein
Raw tokenHAMP:158:0.00000000000209:227:70:69
2 HisKA#2
232-291 aa · 60 aa · 13.1% of protein
Raw tokenHisKA:232:0.000000000957:291:60:64
3 HATPase_c#3
340-453 aa · 114 aa · 24.8% of protein
Raw tokenHATPase_c:340:2.21e-25:453:115:109
  • Raw architecture: HAMP:158:0.00000000000209:227:70:69#HisKA:232:0.000000000957:291:60:64#HATPase_c:340:2.21e-25:453:115:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834359.1::G00033
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span337417-338796Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_01741RefSeq proteinWP_003498628.1
Context group IDGCF_000189615::NZ_GL834359.1::G00033
Context members
HMPREF9475_RS08840
Partner locus tags
HMPREF9475_RS08840
Partner old locus tags
HMPREF9475_01741
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003498628.1Primary protein accession used for annex mappings.
UniProt accessionE7GIS1Primary UniProt accession resolved in the annex database.
UniProt IDE7GIS1_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS08840Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_01741Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834359.1Sequence record reported by the local genomic context database.
Genomic interval337 417-338 796 nt1 380 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span337 417-338 796 ntGCF_000189615::NZ_GL834359.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834359.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834359.1All displayed genes belong to this local TCS context.
Neighborhood span337 417-338 796 nt1 380 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
337 417 nt338 796 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1845579Run 6 · HK · 47 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS04240Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1845579

Simplified PFAM architecture for HKOC_1845579

PFAM domain coverage: 218 / 459 aa (47.5%)

1 aa459 aa
HAMP: 181-226 aaHAMPHisKA: 233-291 aaHisKAHATPase_c: 341-453 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[181-226] | HisKA[233-291] | HATPase_c[341-453]
  • Domain count: 3
  • Matched identifier: HKOC_1845579
  • Positioned domains: HAMP 181-226 ; HisKA 233-291 ; HATPase_c 341-453
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS04240

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key