Gene detail

HMPREF9475_RS07690

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength875 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS07690Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0453055Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_003507697.1 · MIST4 HMPREF9475_RS07690RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3GGDEFHisKAHATPase_cResponse_reg
Protein length875 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage513 / 875 aa (58.6%)Merged over positioned domains only.
Domain description1 PAS_3,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa875 aa
PAS_3: 69-127 aa (59 aa)1GGDEF: 144-290 aa (147 aa)2HisKA: 496-562 aa (67 aa)3HATPase_c: 608-729 aa (122 aa)4Response_reg: 755-872 aa (118 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
69-127 aa · 59 aa · 6.7% of protein
Raw tokenPAS_3:69:0.0000245:127:63:89
2 GGDEF#2
144-290 aa · 147 aa · 16.8% of protein
Raw tokenGGDEF:144:0.0000000000101:290:159:160
3 HisKA#3
496-562 aa · 67 aa · 7.7% of protein
Raw tokenHisKA:496:1.46e-16:562:67:64
4 HATPase_c#4
608-729 aa · 122 aa · 13.9% of protein
Raw tokenHATPase_c:608:2.45e-28:729:122:109
5 Response_reg#5
755-872 aa · 118 aa · 13.5% of protein
Raw tokenResponse_reg:755:3.76e-31:872:118:111
  • Raw architecture: PAS_3:69:0.0000245:127:63:89#GGDEF:144:0.0000000000101:290:159:160#HisKA:496:1.46e-16:562:67:64#HATPase_c:608:2.45e-28:729:122:109#Response_reg:755:3.76e-31:872:118:111
  • Domain description: 1 PAS_3,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834359.1::G00031
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span70649-73276Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_01509RefSeq proteinWP_003507697.1
Context group IDGCF_000189615::NZ_GL834359.1::G00031
Context members
HMPREF9475_RS07690
Partner locus tags
HMPREF9475_RS07690
Partner old locus tags
HMPREF9475_01509
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003507697.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS07690Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_01509Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834359.1Sequence record reported by the local genomic context database.
Genomic interval70 649-73 276 nt2 628 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span70 649-73 276 ntGCF_000189615::NZ_GL834359.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834359.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834359.1All displayed genes belong to this local TCS context.
Neighborhood span70 649-73 276 nt2 628 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
70 649 nt73 276 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0453055Run 6 · HK · 2 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS07690The current gene is the representative for this cluster.
PFAM architectureGGDEF + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0453055

Simplified PFAM architecture for HKOC_0453055

PFAM domain coverage: 459 / 875 aa (52.5%)

1 aa875 aa
GGDEF: 145-298 aaGGDEFHisKA: 497-562 aaHisKAHATPase_c: 609-729 aaHATPase_cResponse_reg: 755-872 aaResponse_reg
GGDEFHisKAHATPase_cResponse_reg
  • Simplified architecture: GGDEF + HisKA + HATPase_c + Response_reg
  • Raw architecture: GGDEF[145-298] | HisKA[497-562] | HATPase_c[609-729] | Response_reg[755-872]
  • Domain count: 4
  • Matched identifier: HKOC_0453055
  • Positioned domains: GGDEF 145-298 ; HisKA 497-562 ; HATPase_c 609-729 ; Response_reg 755-872
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS07690

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key