Gene detail

HMPREF9475_RS07070

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength1107 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS07070Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0228172Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_207733386.1 · MIST4 HMPREF9475_RS07070RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3PAS_9HisKAHATPase_cResponse_reg
Protein length1107 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage598 / 1107 aa (54.0%)Merged over positioned domains only.
Domain description1 PAS_3,1 PAS_9,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1107 aa
PAS_3: 203-285 aa (83 aa)1PAS_9: 323-430 aa (108 aa)2HisKA: 594-660 aa (67 aa)3HATPase_c: 707-822 aa (116 aa)4Response_reg: 846-951 aa (106 aa)5Response_reg: 986-1103 aa (118 aa)6
Domain-by-domain annotation6 items
1 PAS_3#1
203-285 aa · 83 aa · 7.5% of protein
Raw tokenPAS_3:203:0.000000000000612:285:83:89
2 PAS_9#2
323-430 aa · 108 aa · 9.8% of protein
Raw tokenPAS_9:323:0.00000000000257:430:116:102
3 HisKA#3
594-660 aa · 67 aa · 6.1% of protein
Raw tokenHisKA:594:1.1e-16:660:67:64
4 HATPase_c#4
707-822 aa · 116 aa · 10.5% of protein
Raw tokenHATPase_c:707:5.47e-31:822:116:109
5 Response_reg#5
846-951 aa · 106 aa · 9.6% of protein
Raw tokenResponse_reg:846:2.45e-18:951:106:111
6 Response_reg#6
986-1103 aa · 118 aa · 10.7% of protein
Raw tokenResponse_reg:986:1.63e-29:1103:118:111
  • Raw architecture: PAS_3:203:0.000000000000612:285:83:89#PAS_9:323:0.00000000000257:430:116:102#HisKA:594:1.1e-16:660:67:64#HATPase_c:707:5.47e-31:822:116:109#Response_reg:846:2.45e-18:951:106:111#Response_reg:986:1.63e-29:1103:118:111
  • Domain description: 1 PAS_3,1 PAS_9,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834358.1::G00029
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span624648-627926Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_01390RefSeq proteinWP_207733386.1
Context group IDGCF_000189615::NZ_GL834358.1::G00029
Context members
HMPREF9475_RS07070
Partner locus tags
HMPREF9475_RS07070
Partner old locus tags
HMPREF9475_01390
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_207733386.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS07070Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_01390Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834358.1Sequence record reported by the local genomic context database.
Genomic interval624 648-627 926 nt3 279 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span624 648-627 926 ntGCF_000189615::NZ_GL834358.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834358.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834358.1All displayed genes belong to this local TCS context.
Neighborhood span624 648-627 926 nt3 279 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
624 648 nt627 926 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0228172Run 6 · HK · 4 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS07070The current gene is the representative for this cluster.
PFAM architectureSnoaL_3 + PAS_3 + PAS_9 + HisKA + HATPase_c + Response_reg + Response_reg7 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0228172

Simplified PFAM architecture for HKOC_0228172

PFAM domain coverage: 711 / 1107 aa (64.2%)

1 aa1107 aa
SnoaL_3: 32-146 aaSnoaL_3PAS_3: 203-282 aaPAS_3PAS_9: 324-430 aaPAS_9HisKA: 594-660 aaHisKAHATPase_c: 707-822 aaHATPase_cResponse_reg: 846-954 aaResponse_regResponse_reg: 986-1102 aaResponse_reg
SnoaL_3PAS_3PAS_9HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: SnoaL_3 + PAS_3 + PAS_9 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: SnoaL_3[32-146] | PAS_3[203-282] | PAS_9[324-430] | HisKA[594-660] | HATPase_c[707-822] | Response_reg[846-954] | Response_reg[986-1102]
  • Domain count: 7
  • Matched identifier: HKOC_0228172
  • Positioned domains: SnoaL_3 32-146 ; PAS_3 203-282 ; PAS_9 324-430 ; HisKA 594-660 ; HATPase_c 707-822 ; Response_reg 846-954 ; Response_reg 986-1102
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS07070

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key