Gene detail

HMPREF9475_RS06580

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength1207 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS06580Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0154436Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_003507396.1 · MIST4 HMPREF9475_RS06580RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length1207 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage582 / 1207 aa (48.2%)Merged over positioned domains only.
Domain description2 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1207 aa
PAS_3: 172-252 aa (81 aa)1PAS_3: 294-378 aa (85 aa)2HisKA: 677-743 aa (67 aa)3HATPase_c: 790-907 aa (118 aa)4Response_reg: 930-1043 aa (114 aa)5Response_reg: 1071-1187 aa (117 aa)6
Domain-by-domain annotation6 items
1 PAS_3#1
172-252 aa · 81 aa · 6.7% of protein
Raw tokenPAS_3:172:8.51e-18:252:81:89
2 PAS_3#2
294-378 aa · 85 aa · 7.0% of protein
Raw tokenPAS_3:294:0.00000000000000794:378:85:89
3 HisKA#3
677-743 aa · 67 aa · 5.6% of protein
Raw tokenHisKA:677:9.12e-16:743:67:64
4 HATPase_c#4
790-907 aa · 118 aa · 9.8% of protein
Raw tokenHATPase_c:790:1.74e-30:907:119:109
5 Response_reg#5
930-1043 aa · 114 aa · 9.4% of protein
Raw tokenResponse_reg:930:2.16e-20:1043:114:111
6 Response_reg#6
1071-1187 aa · 117 aa · 9.7% of protein
Raw tokenResponse_reg:1071:1.26e-24:1187:117:111
  • Raw architecture: PAS_3:172:8.51e-18:252:81:89#PAS_3:294:0.00000000000000794:378:85:89#HisKA:677:9.12e-16:743:67:64#HATPase_c:790:1.74e-30:907:119:109#Response_reg:930:2.16e-20:1043:114:111#Response_reg:1071:1.26e-24:1187:117:111
  • Domain description: 2 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834358.1::G00028
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span513100-516723Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_01295RefSeq proteinWP_003507396.1
Context group IDGCF_000189615::NZ_GL834358.1::G00028
Context members
HMPREF9475_RS06580
Partner locus tags
HMPREF9475_RS06580
Partner old locus tags
HMPREF9475_01295
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003507396.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS06580Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_01295Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834358.1Sequence record reported by the local genomic context database.
Genomic interval513 100-516 723 nt3 624 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span513 100-516 723 ntGCF_000189615::NZ_GL834358.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834358.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834358.1All displayed genes belong to this local TCS context.
Neighborhood span513 100-516 723 nt3 624 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
513 100 nt516 723 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0154436Run 6 · HK · 5 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS06580The current gene is the representative for this cluster.
PFAM architecturePAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg6 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0154436

Simplified PFAM architecture for HKOC_0154436

PFAM domain coverage: 576 / 1207 aa (47.7%)

1 aa1207 aa
PAS_3: 172-253 aaPAS_3PAS_3: 295-374 aaPAS_3HisKA: 677-743 aaHisKAHATPase_c: 790-905 aaHATPase_cResponse_reg: 930-1043 aaResponse_regResponse_reg: 1071-1187 aaResponse_reg
PAS_3PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[172-253] | PAS_3[295-374] | HisKA[677-743] | HATPase_c[790-905] | Response_reg[930-1043] | Response_reg[1071-1187]
  • Domain count: 6
  • Matched identifier: HKOC_0154436
  • Positioned domains: PAS_3 172-253 ; PAS_3 295-374 ; HisKA 677-743 ; HATPase_c 790-905 ; Response_reg 930-1043 ; Response_reg 1071-1187
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS06580

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key